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FBN1 fibrillin 1 [ Chelonia mydas (Green sea turtle) ]

Gene ID: 102947546, updated on 10-Mar-2024

Summary

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Gene symbol
FBN1
Gene description
fibrillin 1
Locus tag
UY3_13715
See related
EnsemblRapid:ENSCMYG00015011276
Gene type
protein coding
RefSeq status
MODEL
Organism
Chelonia mydas
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Americhelydia; Chelonioidea; Cheloniidae; Chelonia
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
69
Annotation release Status Assembly Chr Location
103 current rCheMyd1.pri.v2 (GCF_015237465.2) 10 NC_051250.2 (63585465..63801663, complement)
102 previous assembly rCheMyd1.pri (GCF_015237465.1) 10 NC_051250.1 (20252668..20468786)

Chromosome 10 - NC_051250.2Genomic Context describing neighboring genes Neighboring gene solute carrier family 12 member 1 Neighboring gene deoxyuridine triphosphatase Neighboring gene uncharacterized LOC119567176 Neighboring gene centrosomal protein 152 Neighboring gene SHC adaptor protein 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sea turtle fibropapilloma tumors share genomic drivers and therapeutic vulnerabilities with human cancers. Duffy DJ, et al. Commun Biol, 2018. PMID 30271945, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
fibrillin-1
Names
Fibrillin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Chelonia mydas Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference rCheMyd1.pri.v2 Primary Assembly

Genomic

  1. NC_051250.2 Reference rCheMyd1.pri.v2 Primary Assembly

    Range
    63585465..63801663 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_043524453.1 → XP_043380388.1  fibrillin-1 isoform X1

    UniProtKB/TrEMBL
    M7AUL7
    Conserved Domains (10) summary
    smart00179
    Location:1804 → 1836
    EGF_CA; Calcium-binding EGF-like domain
    cd00054
    Location:761 → 802
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam07645
    Location:1926 → 1967
    EGF_CA; Calcium-binding EGF domain
    pfam00683
    Location:1545 → 1586
    TB; TB domain
    pfam12662
    Location:2461 → 2484
    cEGF; Complement Clr-like EGF-like
    pfam12947
    Location:1363 → 1398
    EGF_3; EGF domain
    pfam14670
    Location:1197 → 1232
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    pfam18193
    Location:55 → 86
    Fibrillin_U_N; Fibrillin 1 unique N-terminal domain
    cl00057
    Location:2001 → 2047
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    cl21504
    Location:2481 → 2512
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

  2. XM_037910538.2 → XP_037766466.1  fibrillin-1 isoform X1

    UniProtKB/TrEMBL
    M7AUL7
    Conserved Domains (10) summary
    smart00179
    Location:1804 → 1836
    EGF_CA; Calcium-binding EGF-like domain
    cd00054
    Location:761 → 802
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam07645
    Location:1926 → 1967
    EGF_CA; Calcium-binding EGF domain
    pfam00683
    Location:1545 → 1586
    TB; TB domain
    pfam12662
    Location:2461 → 2484
    cEGF; Complement Clr-like EGF-like
    pfam12947
    Location:1363 → 1398
    EGF_3; EGF domain
    pfam14670
    Location:1197 → 1232
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    pfam18193
    Location:55 → 86
    Fibrillin_U_N; Fibrillin 1 unique N-terminal domain
    cl00057
    Location:2001 → 2047
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    cl21504
    Location:2481 → 2512
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

  3. XM_037910540.2 → XP_037766468.1  fibrillin-1 isoform X1

    UniProtKB/TrEMBL
    M7AUL7
    Related
    ENSCMYP00015017583.1, ENSCMYT00015021224.1
    Conserved Domains (10) summary
    smart00179
    Location:1804 → 1836
    EGF_CA; Calcium-binding EGF-like domain
    cd00054
    Location:761 → 802
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam07645
    Location:1926 → 1967
    EGF_CA; Calcium-binding EGF domain
    pfam00683
    Location:1545 → 1586
    TB; TB domain
    pfam12662
    Location:2461 → 2484
    cEGF; Complement Clr-like EGF-like
    pfam12947
    Location:1363 → 1398
    EGF_3; EGF domain
    pfam14670
    Location:1197 → 1232
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    pfam18193
    Location:55 → 86
    Fibrillin_U_N; Fibrillin 1 unique N-terminal domain
    cl00057
    Location:2001 → 2047
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    cl21504
    Location:2481 → 2512
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

  4. XM_043524452.1 → XP_043380387.1  fibrillin-1 isoform X1

    UniProtKB/TrEMBL
    M7AUL7
    Conserved Domains (10) summary
    smart00179
    Location:1804 → 1836
    EGF_CA; Calcium-binding EGF-like domain
    cd00054
    Location:761 → 802
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam07645
    Location:1926 → 1967
    EGF_CA; Calcium-binding EGF domain
    pfam00683
    Location:1545 → 1586
    TB; TB domain
    pfam12662
    Location:2461 → 2484
    cEGF; Complement Clr-like EGF-like
    pfam12947
    Location:1363 → 1398
    EGF_3; EGF domain
    pfam14670
    Location:1197 → 1232
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    pfam18193
    Location:55 → 86
    Fibrillin_U_N; Fibrillin 1 unique N-terminal domain
    cl00057
    Location:2001 → 2047
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    cl21504
    Location:2481 → 2512
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

  5. XM_037910541.2 → XP_037766469.1  fibrillin-1 isoform X2

    Conserved Domains (9) summary
    smart00179
    Location:1236 → 1268
    EGF_CA; Calcium-binding EGF-like domain
    cd00054
    Location:193 → 234
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam07645
    Location:1358 → 1399
    EGF_CA; Calcium-binding EGF domain
    pfam00683
    Location:977 → 1018
    TB; TB domain
    pfam12662
    Location:1893 → 1916
    cEGF; Complement Clr-like EGF-like
    pfam12947
    Location:795 → 830
    EGF_3; EGF domain
    pfam14670
    Location:629 → 664
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl00057
    Location:1433 → 1479
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    cl21504
    Location:1913 → 1944
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

  6. XM_037910542.2 → XP_037766470.1  fibrillin-1 isoform X2

    Conserved Domains (9) summary
    smart00179
    Location:1236 → 1268
    EGF_CA; Calcium-binding EGF-like domain
    cd00054
    Location:193 → 234
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam07645
    Location:1358 → 1399
    EGF_CA; Calcium-binding EGF domain
    pfam00683
    Location:977 → 1018
    TB; TB domain
    pfam12662
    Location:1893 → 1916
    cEGF; Complement Clr-like EGF-like
    pfam12947
    Location:795 → 830
    EGF_3; EGF domain
    pfam14670
    Location:629 → 664
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl00057
    Location:1433 → 1479
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    cl21504
    Location:1913 → 1944
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
Nucleotide Protein
Heading Accession and Version

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