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APAF1 apoptotic peptidase activating factor 1 [ Elephantulus edwardii (Cape elephant shrew) ]

Gene ID: 102873514, updated on 10-Mar-2024

Summary

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Gene symbol
APAF1
Gene description
apoptotic peptidase activating factor 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Elephantulus edwardii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Macroscelidea; Macroscelididae; Elephantulus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
26
Annotation release Status Assembly Chr Location
100 current EleEdw1.0 (GCF_000299155.1) Unplaced Scaffold NW_006399818.1 (6270122..6398145)

NW_006399818.1Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase-like Neighboring gene solute carrier family 25 member 3 Neighboring gene IKBKB interacting protein Neighboring gene ankyrin repeat and sterile alpha motif domain containing 1B Neighboring gene HAUS augmin-like complex, subunit 1 pseudogene Neighboring gene golgi associated RAB2 interactor family member 6

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_006399818 unplaced scaffold reference EleEdw1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ADP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in apoptotic signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of apoptosome IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
apoptotic protease-activating factor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Elephantulus edwardii Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EleEdw1.0

Genomic

  1. NW_006399818.1 Reference EleEdw1.0

    Range
    6270122..6398145
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006888505.1 → XP_006888567.1  apoptotic protease-activating factor 1

    Conserved Domains (6) summary
    COG2319
    Location:713 → 1193
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:607 → 899
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    pfam00931
    Location:129 → 414
    NB-ARC; NB-ARC domain
    pfam13191
    Location:126 → 245
    AAA_16; AAA ATPase domain
    sd00039
    Location:660 → 697
    7WD40; WD40 repeat [structural motif]

  2. XM_006888503.1 → XP_006888565.1  apoptotic protease-activating factor 1

    Conserved Domains (6) summary
    COG2319
    Location:651 → 1035
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:607 → 910
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    pfam00931
    Location:129 → 414
    NB-ARC; NB-ARC domain
    pfam13191
    Location:126 → 245
    AAA_16; AAA ATPase domain
    sd00039
    Location:660 → 697
    7WD40; WD40 repeat [structural motif]

  3. XM_006888504.1 → XP_006888566.1  apoptotic protease-activating factor 1

    Conserved Domains (6) summary
    COG2319
    Location:640 → 1024
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:596 → 899
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    pfam00931
    Location:118 → 403
    NB-ARC; NB-ARC domain
    pfam13191
    Location:115 → 234
    AAA_16; AAA ATPase domain
    sd00039
    Location:649 → 686
    7WD40; WD40 repeat [structural motif]

  4. XM_006888506.1 → XP_006888568.1  apoptotic protease-activating factor 1

    Conserved Domains (6) summary
    COG2319
    Location:702 → 1182
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:596 → 888
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    pfam00931
    Location:118 → 403
    NB-ARC; NB-ARC domain
    pfam13191
    Location:115 → 234
    AAA_16; AAA ATPase domain
    sd00039
    Location:649 → 686
    7WD40; WD40 repeat [structural motif]

  5. XM_006888508.1 → XP_006888570.1  apoptotic protease-activating factor 1

    Conserved Domains (2) summary
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    pfam13191
    Location:126 → 245
    AAA_16; AAA ATPase domain

  6. XM_006888507.1 → XP_006888569.1  apoptotic protease-activating factor 1

    Conserved Domains (6) summary
    COG2319
    Location:651 → 1074
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:607 → 899
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    pfam00931
    Location:129 → 414
    NB-ARC; NB-ARC domain
    pfam13191
    Location:126 → 245
    AAA_16; AAA ATPase domain
    sd00039
    Location:660 → 697
    7WD40; WD40 repeat [structural motif]
Nucleotide Protein
Heading Accession and Version

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