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SOCS5 suppressor of cytokine signaling 5 [ Elephantulus edwardii (Cape elephant shrew) ]

Gene ID: 102854860, updated on 11-Apr-2024

Summary

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Gene symbol
SOCS5
Gene description
suppressor of cytokine signaling 5
Gene type
protein coding
RefSeq status
MODEL
Organism
Elephantulus edwardii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Macroscelidea; Macroscelididae; Elephantulus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
1
Annotation release Status Assembly Chr Location
100 current EleEdw1.0 (GCF_000299155.1) Unplaced Scaffold NW_006399761.1 (4408971..4410584)

NW_006399761.1Genomic Context describing neighboring genes Neighboring gene ras homolog family member Q Neighboring gene phosphatidylinositol glycan anchor biosynthesis class F Neighboring gene CXXC repeat containing interactor of PDZ3 domain Neighboring gene proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 pseudogene Neighboring gene multiple coagulation factor deficiency 2, ER cargo receptor complex subunit

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_006399761 unplaced scaffold reference EleEdw1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in epidermal growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
suppressor of cytokine signaling 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Elephantulus edwardii Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EleEdw1.0

Genomic

  1. NW_006399761.1 Reference EleEdw1.0

    Range
    4408971..4410584
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006880895.1 → XP_006880957.1  suppressor of cytokine signaling 5

    Conserved Domains (3) summary
    cd03739
    Location:480 → 535
    SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
    pfam12610
    Location:145 → 196
    SOCS; Suppressor of cytokine signalling
    cl15255
    Location:371 → 471
    SH2; Src homology 2 (SH2) domain
Nucleotide Protein
Heading Accession and Version

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