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RAPGEF5 Rap guanine nucleotide exchange factor 5 [ Myotis lucifugus (little brown bat) ]

Gene ID: 102432406, updated on 30-Mar-2024

Summary

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Gene symbol
RAPGEF5
Gene description
Rap guanine nucleotide exchange factor 5
Gene type
protein coding
RefSeq status
MODEL
Organism
Myotis lucifugus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae; Myotis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
26
Annotation release Status Assembly Chr Location
102 current Myoluc2.0 (GCF_000147115.1) Unplaced Scaffold NW_005871100.1 (6710238..6906541)

NW_005871100.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene renin receptor pseudogene Neighboring gene uncharacterized LOC106697177 Neighboring gene small ubiquitin-related modifier 3 pseudogene Neighboring gene uncharacterized LOC106697179 Neighboring gene U2 spliceosomal RNA Neighboring gene dynein heavy chain 11, axonemal Neighboring gene cell division cycle associated 7 like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005871100 Unplaced Scaffold Reference Myoluc2.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Ras protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rap guanine nucleotide exchange factor 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Myotis lucifugus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Myoluc2.0

Genomic

  1. NW_005871100.1 Reference Myoluc2.0

    Range
    6710238..6906541
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023753857.1 → XP_023609625.1  rap guanine nucleotide exchange factor 5 isoform X1

    Conserved Domains (4) summary
    smart00147
    Location:606 → 819
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases
    smart00229
    Location:320 → 480
    RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
    cd04437
    Location:54 → 176
    DEP_Epac; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in Epac-like proteins. Epac (exchange proteins directly activated by cAMP) proteins are GEFs (guanine-nucleotide-exchange factors) for the small GTPases, Rap1 and Rap2. They are directly regulated by ...
    cl25424
    Location:524 → 600
    TGS; The TGS domain, named after the ThrRS, GTPase, and SpoT/RelA proteins where it occurs, is structurally similar to ubiquitin. TGS is a small domain of about 50 amino acid residues with a predominantly beta-sheet structure. There is no direct information ...

  2. XM_014455916.2 → XP_014311402.1  rap guanine nucleotide exchange factor 5 isoform X2

    Conserved Domains (4) summary
    smart00147
    Location:577 → 790
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases
    smart00229
    Location:320 → 451
    RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
    cd04437
    Location:54 → 176
    DEP_Epac; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in Epac-like proteins. Epac (exchange proteins directly activated by cAMP) proteins are GEFs (guanine-nucleotide-exchange factors) for the small GTPases, Rap1 and Rap2. They are directly regulated by ...
    cl00155
    Location:495 → 571
    UBQ; Ubiquitin-like proteins
Nucleotide Protein
Heading Accession and Version

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