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JAG1 jagged canonical Notch ligand 1 [ Myotis lucifugus (little brown bat) ]

Gene ID: 102418962, updated on 30-Mar-2024

Summary

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Gene symbol
JAG1
Gene description
jagged canonical Notch ligand 1
See related
Ensembl:ENSMLUG00000009421
Gene type
protein coding
RefSeq status
MODEL
Organism
Myotis lucifugus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae; Myotis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
27
Annotation release Status Assembly Chr Location
102 current Myoluc2.0 (GCF_000147115.1) Unplaced Scaffold NW_005871090.1 (1535958..1570910, complement)

NW_005871090.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111825843 Neighboring gene SLX4 interacting protein Neighboring gene 60S ribosomal protein L27a-like Neighboring gene U1 small nuclear ribonucleoprotein C pseudogene

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005871090 Unplaced Scaffold Reference Myoluc2.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Notch binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell communication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment or maintenance of epithelial cell apical/basal polarity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein jagged-1
Names
jagged 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Myotis lucifugus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Myoluc2.0

Genomic

  1. NW_005871090.1 Reference Myoluc2.0

    Range
    1535958..1570910 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023753185.1 → XP_023608953.1  protein jagged-1 isoform X4

    UniProtKB/TrEMBL
    G1PDP3
    Conserved Domains (5) summary
    smart00215
    Location:746 → 813
    VWC_out; von Willebrand factor (vWF) type C domain
    cd00054
    Location:512 → 548
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00008
    Location:631 → 660
    EGF; EGF-like domain
    pfam01414
    Location:126 → 188
    DSL; Delta serrate ligand
    pfam07657
    Location:1 → 66
    MNNL; N terminus of Notch ligand

  2. XM_023753184.1 → XP_023608952.1  protein jagged-1 isoform X2

    UniProtKB/TrEMBL
    G1PDP3
    Conserved Domains (5) summary
    smart00215
    Location:784 → 851
    VWC_out; von Willebrand factor (vWF) type C domain
    cd00054
    Location:550 → 586
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00008
    Location:669 → 698
    EGF; EGF-like domain
    pfam01414
    Location:126 → 188
    DSL; Delta serrate ligand
    pfam07657
    Location:1 → 66
    MNNL; N terminus of Notch ligand

  3. XM_014455112.1 → XP_014310598.1  protein jagged-1 isoform X3

    UniProtKB/TrEMBL
    G1PDP3
    Conserved Domains (5) summary
    smart00215
    Location:767 → 834
    VWC_out; von Willebrand factor (vWF) type C domain
    cd00054
    Location:533 → 569
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00008
    Location:652 → 681
    EGF; EGF-like domain
    pfam01414
    Location:126 → 188
    DSL; Delta serrate ligand
    pfam07657
    Location:1 → 65
    MNNL; N terminus of Notch ligand

  4. XM_014455111.1 → XP_014310597.1  protein jagged-1 isoform X1

    UniProtKB/TrEMBL
    G1PDP3
    Related
    ENSMLUP00000008601.2, ENSMLUT00000009437.2
    Conserved Domains (5) summary
    smart00215
    Location:822 → 889
    VWC_out; von Willebrand factor (vWF) type C domain
    cd00054
    Location:588 → 624
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00008
    Location:707 → 736
    EGF; EGF-like domain
    pfam01414
    Location:126 → 188
    DSL; Delta serrate ligand
    pfam07657
    Location:1 → 65
    MNNL; N terminus of Notch ligand

  5. XM_006087959.3 → XP_006088021.1  protein jagged-1 isoform X1

    UniProtKB/TrEMBL
    G1PDP3
    Conserved Domains (5) summary
    smart00215
    Location:822 → 889
    VWC_out; von Willebrand factor (vWF) type C domain
    cd00054
    Location:588 → 624
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00008
    Location:707 → 736
    EGF; EGF-like domain
    pfam01414
    Location:126 → 188
    DSL; Delta serrate ligand
    pfam07657
    Location:1 → 65
    MNNL; N terminus of Notch ligand

  6. XM_023753186.1 → XP_023608954.1  protein jagged-1 isoform X5

    UniProtKB/TrEMBL
    G1PDP3
    Conserved Domains (4) summary
    smart00215
    Location:704 → 771
    VWC_out; von Willebrand factor (vWF) type C domain
    cd00054
    Location:470 → 506
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00008
    Location:589 → 618
    EGF; EGF-like domain
    pfam01414
    Location:8 → 70
    DSL; Delta serrate ligand

  7. XM_023753187.1 → XP_023608955.1  protein jagged-1 isoform X6

    Conserved Domains (3) summary
    smart00215
    Location:686 → 753
    VWC_out; von Willebrand factor (vWF) type C domain
    cd00054
    Location:452 → 488
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00008
    Location:571 → 600
    EGF; EGF-like domain
Nucleotide Protein
Heading Accession and Version

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