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PIKFYVE phosphoinositide kinase, FYVE-type zinc finger containing [ Alligator sinensis (Chinese alligator) ]

Gene ID: 102388365, updated on 10-Mar-2024

Summary

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Gene symbol
PIKFYVE
Gene description
phosphoinositide kinase, FYVE-type zinc finger containing
Gene type
protein coding
RefSeq status
MODEL
Organism
Alligator sinensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae; Alligator
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
43
Annotation release Status Assembly Chr Location
102 current ASM45574v1 (GCF_000455745.1) Unplaced Scaffold NW_005842359.1 (645996..742239)

NW_005842359.1Genomic Context describing neighboring genes Neighboring gene shugoshin 1-like Neighboring gene isocitrate dehydrogenase (NADP(+)) 1 Neighboring gene parathyroid hormone 2 receptor Neighboring gene uncharacterized LOC102388621

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005842359 Unplaced Scaffold Reference ASM45574v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-phosphate 5-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 3-phosphate 5-kinase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Alligator sinensis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM45574v1 Primary Assembly

Genomic

  1. NW_005842359.1 Reference ASM45574v1 Primary Assembly

    Range
    645996..742239
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025210576.1 → XP_025066361.1  1-phosphatidylinositol 3-phosphate 5-kinase

    UniProtKB/TrEMBL
    A0A3Q0H2T4
    Conserved Domains (4) summary
    cd00139
    Location:1800 → 2113
    PIPKc; Phosphatidylinositol phosphate kinases (PIPK) catalyze the phosphorylation of phosphatidylinositol phosphate on the fourth or fifth hydroxyl of the inositol ring, to form phosphatidylinositol bisphosphate. CD alignment includes type II ...
    cd03334
    Location:628 → 888
    Fab1_TCP; TCP-1 like domain of the eukaryotic phosphatidylinositol 3-phosphate (PtdIns3P) 5-kinase Fab1. Fab1p is important for vacuole size regulation, presumably by modulating PtdIns(3,5)P2 effector activity. In the human homolog p235/PIKfyve deletion of this ...
    cd04448
    Location:367 → 448
    DEP_PIKfyve; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in fungal RhoGEF (GDP/GTP exchange factor) PIKfyve-like proteins. PIKfyve contains N-terminal Fyve finger and DEP domains, a central chaperonin-like domain and a C-terminal PIPK (phosphatidylinositol ...
    cd15725
    Location:164 → 225
    FYVE_PIKfyve_Fab1; FYVE domain found in metazoan PIKfyve, fungal and plant Fab1, and similar proteins
Nucleotide Protein
Heading Accession and Version

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