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ABL2 c-abl oncogene 2, non-receptor tyrosine kinase [ Latimeria chalumnae (coelacanth) ]

Gene ID: 102352150, updated on 30-Apr-2024

Summary

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Gene symbol
ABL2
Gene description
c-abl oncogene 2, non-receptor tyrosine kinase
See related
Ensembl:ENSLACG00000005659
Gene type
protein coding
RefSeq status
MODEL
Organism
Latimeria chalumnae
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Coelacanthiformes; Coelacanthidae; Latimeria
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: 6
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_04 current fLatCha1.pri (GCF_037176945.1) 6 NC_088144.1 (100636866..100716597, complement)
101 previous assembly LatCha1 (GCF_000225785.1) Unplaced Scaffold NW_005820147.1 (179108..258263, complement)

Chromosome 6 - NC_088144.1Genomic Context describing neighboring genes Neighboring gene deleted in malignant brain tumors 1 protein-like Neighboring gene uncharacterized LOC135357562 Neighboring gene torsin family 3, member A Neighboring gene FAM20B glycosaminoglycan xylosylkinase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase ABL2
Names
ABL proto-oncogene 2, non-receptor tyrosine kinase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_037176945.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fLatCha1.pri

Genomic

  1. NC_088144.1 Reference fLatCha1.pri

    Range
    100636866..100716597 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006005063.1 → XP_006005125.1  tyrosine-protein kinase ABL2 isoform X1

    UniProtKB/TrEMBL
    H3A9Q6
    Related
    ENSLACP00000006377.1, ENSLACT00000006430.1
    Conserved Domains (5) summary
    smart00808
    Location:1055 → 1175
    FABD; F-actin binding domain (FABD)
    cd09935
    Location:152 → 245
    SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
    cd11850
    Location:94 → 147
    SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
    cd05052
    Location:264 → 526
    PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase
    pfam07714
    Location:271 → 522
    Pkinase_Tyr; Protein tyrosine kinase

  2. XM_006005064.1 → XP_006005126.1  tyrosine-protein kinase ABL2 isoform X2

    Conserved Domains (5) summary
    smart00808
    Location:1035 → 1155
    FABD; F-actin binding domain (FABD)
    cd09935
    Location:132 → 225
    SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
    cd11850
    Location:74 → 127
    SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
    cd05052
    Location:244 → 506
    PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase
    pfam07714
    Location:251 → 502
    Pkinase_Tyr; Protein tyrosine kinase
Nucleotide Protein
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