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MAGI3A membrane associated guanylate kinase, WW and PDZ domain containing 3a [ Latimeria chalumnae (coelacanth) ]

Gene ID: 102348191, updated on 2-May-2024

Summary

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Gene symbol
MAGI3A
Gene description
membrane associated guanylate kinase, WW and PDZ domain containing 3a
See related
Ensembl:ENSLACG00000016389
Gene type
protein coding
RefSeq status
MODEL
Organism
Latimeria chalumnae
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Coelacanthiformes; Coelacanthidae; Latimeria
Also known as
MAGI3
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: 24
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_04 current fLatCha1.pri (GCF_037176945.1) 24 NC_088162.1 (7470864..7660462, complement)
101 previous assembly LatCha1 (GCF_000225785.1) Unplaced Scaffold NW_005819025.1 (1561729..1748940, complement)

Chromosome 24 - NC_088162.1Genomic Context describing neighboring genes Neighboring gene protein PHTF1 Neighboring gene uncharacterized LOC102348018 Neighboring gene leucine-rich repeats and immunoglobulin-like domains 2 Neighboring gene uncharacterized LOC135361133

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3a
Names
membrane associated guanylate kinase, WW and PDZ domain containing 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_037176945.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fLatCha1.pri

Genomic

  1. NC_088162.1 Reference fLatCha1.pri

    Range
    7470864..7660462 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005987620.2 → XP_005987682.1  membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3a isoform X1

    UniProtKB/TrEMBL
    H3B9P2, H3B9P3
    Related
    ENSLACP00000018613.1
    Conserved Domains (7) summary
    PLN00049
    Location:391 → 597
    PLN00049; carboxyl-terminal processing protease; Provisional
    smart00456
    Location:293 → 325
    WW; Domain with 2 conserved Trp (W) residues
    smart00228
    Location:730 → 813
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00201
    Location:341 → 371
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd00992
    Location:1024 → 1104
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam16228
    Location:1358 → 1492
    DUF4887; Domain of unknown function (DUF4887)
    cl17190
    Location:120 → 216
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

  2. XM_005987621.2 → XP_005987683.1  membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3a isoform X2

    UniProtKB/TrEMBL
    H3B9P3
    Related
    ENSLACP00000018614.1
    Conserved Domains (7) summary
    PLN00049
    Location:316 → 522
    PLN00049; carboxyl-terminal processing protease; Provisional
    smart00456
    Location:218 → 250
    WW; Domain with 2 conserved Trp (W) residues
    smart00228
    Location:655 → 738
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00201
    Location:266 → 296
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd00992
    Location:949 → 1029
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam16228
    Location:1283 → 1417
    DUF4887; Domain of unknown function (DUF4887)
    cl17190
    Location:45 → 141
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

  3. XM_005987623.3 → XP_005987685.1  membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3a isoform X4

    Conserved Domains (6) summary
    PLN00049
    Location:391 → 597
    PLN00049; carboxyl-terminal processing protease; Provisional
    smart00456
    Location:293 → 325
    WW; Domain with 2 conserved Trp (W) residues
    smart00228
    Location:730 → 813
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00201
    Location:341 → 371
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd00992
    Location:853 → 938
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl17190
    Location:120 → 216
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

  4. XM_005987622.3 → XP_005987684.1  membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3a isoform X3

    Conserved Domains (6) summary
    PLN00049
    Location:391 → 597
    PLN00049; carboxyl-terminal processing protease; Provisional
    smart00456
    Location:293 → 325
    WW; Domain with 2 conserved Trp (W) residues
    smart00228
    Location:730 → 813
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00201
    Location:341 → 371
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd00992
    Location:1024 → 1104
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl17190
    Location:120 → 216
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
Nucleotide Protein
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