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bace1 beta-secretase 1 [ Haplochromis burtoni (Burton's mouthbrooder) ]

Gene ID: 102290976, updated on 10-Mar-2024

Summary

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Gene symbol
bace1
Gene description
beta-secretase 1
See related
Ensembl:ENSHBUG00000022886
Gene type
protein coding
RefSeq status
MODEL
Organism
Haplochromis burtoni
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids; Pseudocrenilabrinae; Haplochromini; Haplochromis
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: Un
Exon count:
9
Annotation release Status Assembly Chr Location
102 current NCSU_Asbu1 (GCF_018398535.1) Unplaced Scaffold NW_024582645.1 (714616..730509)
101 previous assembly AstBur1.0 (GCF_000239415.1) Unplaced Scaffold NW_005179740.1 (63988..79822, complement)

NW_024582645.1Genomic Context describing neighboring genes Neighboring gene T-box transcription factor 10 Neighboring gene apolipoprotein A-Ib Neighboring gene proprotein convertase subtilisin/kexin type 7 Neighboring gene transgelin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aspartic-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in amyloid-beta metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in membrane protein ectodomain proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in trans-Golgi network IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
beta-secretase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Haplochromis burtoni Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NCSU_Asbu1 Primary Assembly

Genomic

  1. NW_024582645.1 Reference NCSU_Asbu1 Primary Assembly

    Range
    714616..730509
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005942427.2 → XP_005942489.1  beta-secretase 1

    See identical proteins and their annotated locations for XP_005942489.1

    UniProtKB/TrEMBL
    A0A3Q3CER0
    Related
    ENSHBUP00000020592.1
    Conserved Domains (2) summary
    cd05473
    Location:89 → 454
    beta_secretase_like; Beta-secretase, aspartic-acid protease important in the pathogenesis of Alzheimer's disease
    pfam00026
    Location:92 → 433
    Asp; Eukaryotic aspartyl protease
Nucleotide Protein
Heading Accession and Version

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