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CFB complement factor B [ Myotis brandtii (Brandt's bat) ]

Gene ID: 102262757, updated on 30-Mar-2024

Summary

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Gene symbol
CFB
Gene description
complement factor B
Locus tag
D623_10007232
Gene type
protein coding
RefSeq status
MODEL
Organism
Myotis brandtii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae; Myotis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
18
Annotation release Status Assembly Chr Location
101 current ASM41265v1 (GCF_000412655.1) Unplaced Scaffold NW_005354596.1 (302112..308366, complement)

NW_005354596.1Genomic Context describing neighboring genes Neighboring gene SKI2 subunit of superkiller complex Neighboring gene decapping exoribonuclease Neighboring gene negative elongation factor complex member E Neighboring gene uncharacterized LOC106725010 Neighboring gene complement C2 Neighboring gene zinc finger and BTB domain containing 12

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005354596.1 Unplaced Scaffold Reference ASM41265v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in complement activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
complement factor B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Myotis brandtii Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM41265v1

Genomic

  1. NW_005354596.1 Reference ASM41265v1

    Range
    302112..308366 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005859851.2 → XP_005859913.1  complement factor B

    UniProtKB/TrEMBL
    S7P7P2
    Conserved Domains (5) summary
    cd00033
    Location:127 → 182
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00032
    Location:79 → 107
    CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
    cd00190
    Location:512 → 783
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    cd01470
    Location:293 → 490
    vWA_complement_factors; Complement factors B and C2 are two critical proteases for complement activation. They both contain three CCP or Sushi domains, a trypsin-type serine protease domain and a single VWA domain with a conserved metal ion dependent adhesion site referred ...
    pfam00089
    Location:510 → 780
    Trypsin; Trypsin
Nucleotide Protein
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