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hck HCK proto-oncogene, Src family tyrosine kinase [ Xiphophorus maculatus (southern platyfish) ]

Gene ID: 102216930, updated on 11-Apr-2024

Summary

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Gene symbol
hck
Gene description
HCK proto-oncogene, Src family tyrosine kinase
See related
Ensembl:ENSXMAG00000004194
Gene type
protein coding
RefSeq status
MODEL
Organism
Xiphophorus maculatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae; Xiphophorus
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: 1
Exon count:
13
Annotation release Status Assembly Chr Location
102 current X_maculatus-5.0-male (GCF_002775205.1) 1 NC_036443.1 (5069648..5093899)
101 previous assembly Xiphophorus_maculatus-4.4.2 (GCF_000241075.1) Unplaced Scaffold NW_005372303.1 (453841..476641)

Chromosome 1 - NC_036443.1Genomic Context describing neighboring genes Neighboring gene GATA binding protein 5 Neighboring gene retinoblastoma binding protein 8-like Neighboring gene transmembrane 9 superfamily protein member 4 Neighboring gene pleiomorphic adenoma gene-like 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extrinsic component of cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase HCK

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xiphophorus maculatus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference X_maculatus-5.0-male Primary Assembly

Genomic

  1. NC_036443.1 Reference X_maculatus-5.0-male Primary Assembly

    Range
    5069648..5093899
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005804855.2 → XP_005804912.1  tyrosine-protein kinase HCK isoform X1

    UniProtKB/TrEMBL
    M3ZPT8
    Related
    ENSXMAP00000004231.1, ENSXMAT00000004236.2
    Conserved Domains (3) summary
    cl15255
    Location:113 → 216
    SH2; Src homology 2 (SH2) domain
    cl17036
    Location:58 → 108
    SH3; Src Homology 3 domain superfamily
    cl21453
    Location:227 → 498
    PKc_like; Protein Kinases, catalytic domain

  2. XM_023337512.1 → XP_023193280.1  tyrosine-protein kinase HCK isoform X2

    Conserved Domains (3) summary
    cl15255
    Location:99 → 202
    SH2; Src homology 2 (SH2) domain
    cl17036
    Location:44 → 94
    SH3; Src Homology 3 domain superfamily
    cl21453
    Location:213 → 484
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein Strain
Heading Accession and Version

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