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THPO thrombopoietin [ Capra hircus (goat) ]

Gene ID: 102181435, updated on 1-Aug-2024

Summary

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Gene symbol
THPO
Gene description
thrombopoietin
See related
EnsemblRapid:ENSCHIG00000017758
Gene type
protein coding
RefSeq status
MODEL
Organism
Capra hircus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Capra
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
7
Annotation release Status Assembly Chr Location
102 current ASM170441v1 (GCF_001704415.1) 1 NC_030808.1 (82496374..82503155)
101 previous assembly CHIR_1.0 (GCF_000317765.1) 1 NC_022293.1 (81196260..81202579)

Chromosome 1 - NC_030808.1Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 2054 Neighboring gene chordin Neighboring gene RNA polymerase II, I and III subunit H Neighboring gene uncharacterized LOC106502122 Neighboring gene chloride voltage-gated channel 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables hormone activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of hematopoietic stem cell proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in thrombopoietin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
thrombopoietin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Capra hircus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM170441v1 Primary Assembly

Genomic

  1. NC_030808.1 Reference ASM170441v1 Primary Assembly

    Range
    82496374..82503155
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005675181.3 → XP_005675238.1  thrombopoietin isoform X1

    See identical proteins and their annotated locations for XP_005675238.1

    UniProtKB/TrEMBL
    A0A452F1T3, A0A8C2PGD4
    Related
    ENSCHIP00000018239.1, ENSCHIT00000026054.1
    Conserved Domains (1) summary
    pfam00758
    Location:25 → 176
    EPO_TPO; Erythropoietin/thrombopoietin

  2. XM_005675182.3 → XP_005675239.1  thrombopoietin isoform X2

    See identical proteins and their annotated locations for XP_005675239.1

    UniProtKB/TrEMBL
    A0A8C2PGD4, A0AAJ6RY14
    Conserved Domains (1) summary
    pfam00758
    Location:25 → 172
    EPO_TPO; Erythropoietin/thrombopoietin

  3. XM_005675183.3 → XP_005675240.1  thrombopoietin isoform X3

    See identical proteins and their annotated locations for XP_005675240.1

    UniProtKB/TrEMBL
    A0AAJ6RYG4
    Related
    ENSCHIP00000018250.2, ENSCHIT00000026065.2
    Conserved Domains (1) summary
    pfam00758
    Location:25 → 153
    EPO_TPO; Erythropoietin/thrombopoietin
Nucleotide Protein
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