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PHF8 PHD finger protein 8 [ Macaca fascicularis (crab-eating macaque) ]

Gene ID: 102128432, updated on 1-Aug-2024

Summary

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Gene symbol
PHF8
Gene description
PHD finger protein 8
See related
Ensembl:ENSMFAG00000036532
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca fascicularis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: X
Exon count:
25
Annotation release Status Assembly Chr Location
RS_2024_05 current T2T-MFA8v1.0 (GCF_037993035.1) X NC_088395.1 (53909221..54018428, complement)
102 previous assembly MFA1912RKSv2 (GCF_012559485.2) X NC_052275.1 (52844968..52953222, complement)

Chromosome X - NC_088395.1Genomic Context describing neighboring genes Neighboring gene large ribosomal subunit protein bL32m-like Neighboring gene small ribosomal subunit protein bS18m-like Neighboring gene small ribosomal subunit protein uS14-like Neighboring gene family with sequence similarity 120 member C Neighboring gene WNK lysine deficient protein kinase 3 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables histone demethylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription coregulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein demethylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
histone lysine demethylase PHF8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_037993035.1-RS_2024_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MFA8v1.0

Genomic

  1. NC_088395.1 Reference T2T-MFA8v1.0

    Range
    53909221..54018428 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005593667.4 → XP_005593724.1  histone lysine demethylase PHF8 isoform X3

    UniProtKB/TrEMBL
    A0A2K5TJ73
    Conserved Domains (3) summary
    smart00558
    Location:235 → 298
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    cd15642
    Location:42 → 93
    PHD_PHF8; PHD finger found in histone lysine demethylase PHF8
    cl21464
    Location:270 → 370
    cupin_like; Conserved domain found in cupin and related proteins

  2. XM_005593661.4 → XP_005593718.1  histone lysine demethylase PHF8 isoform X1

    See identical proteins and their annotated locations for XP_005593718.1

    UniProtKB/TrEMBL
    A0A2K5TJ99
    Related
    ENSMFAP00000000091.1
    Conserved Domains (3) summary
    smart00558
    Location:235 → 298
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    cd15642
    Location:42 → 93
    PHD_PHF8; PHD finger found in histone lysine demethylase PHF8
    cl21464
    Location:270 → 370
    cupin_like; Conserved domain found in cupin and related proteins

  3. XM_065538242.1 → XP_065394314.1  histone lysine demethylase PHF8 isoform X2

    UniProtKB/TrEMBL
    A0A2K5TJ99

  4. XM_065538243.1 → XP_065394315.1  histone lysine demethylase PHF8 isoform X4

    UniProtKB/TrEMBL
    A0A2K5TJ73

  5. XM_065538241.1 → XP_065394313.1  histone lysine demethylase PHF8 isoform X2

    UniProtKB/TrEMBL
    A0A2K5TJ99

  6. XM_045384310.2 → XP_045240245.1  histone lysine demethylase PHF8 isoform X2

    UniProtKB/TrEMBL
    A0A2K5TJ99
    Conserved Domains (4) summary
    smart00558
    Location:199 → 262
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    cd15642
    Location:6 → 57
    PHD_PHF8; PHD finger found in histone lysine demethylase PHF8
    pfam17811
    Location:338 → 441
    JHD; Jumonji helical domain
    cl40423
    Location:234 → 334
    cupin_RmlC-like; RmlC-like cupin superfamily

  7. XM_005593665.4 → XP_005593722.1  histone lysine demethylase PHF8 isoform X2

    See identical proteins and their annotated locations for XP_005593722.1

    UniProtKB/TrEMBL
    A0A2K5TJ99
    Conserved Domains (4) summary
    smart00558
    Location:199 → 262
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    cd15642
    Location:6 → 57
    PHD_PHF8; PHD finger found in histone lysine demethylase PHF8
    pfam17811
    Location:338 → 441
    JHD; Jumonji helical domain
    cl40423
    Location:234 → 334
    cupin_RmlC-like; RmlC-like cupin superfamily
Nucleotide Protein
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