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Dlg3 discs large MAGUK scaffold protein 3 [ Chinchilla lanigera (long-tailed chinchilla) ]

Gene ID: 102024998, updated on 10-Mar-2024

Summary

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Gene symbol
Dlg3
Gene description
discs large MAGUK scaffold protein 3
See related
Ensembl:ENSCLAG00000015561
Gene type
protein coding
RefSeq status
MODEL
Organism
Chinchilla lanigera
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Chinchillidae; Chinchilla
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
24
Annotation release Status Assembly Chr Location
101 current ChiLan1.0 (GCF_000276665.1) Unplaced Scaffold NW_004955475.1 (9992888..10056197)

NW_004955475.1Genomic Context describing neighboring genes Neighboring gene kinesin family member 4A Neighboring gene glycerophosphodiester phosphodiesterase domain containing 2 Neighboring gene 40S ribosomal protein S24 pseudogene Neighboring gene testis expressed 11 Neighboring gene solute carrier family 7 member 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004955475.1 Unplaced Scaffold Reference ChiLan1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in neuromuscular junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic density membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
disks large homolog 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Chinchilla lanigera Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ChiLan1.0 Primary Assembly

Genomic

  1. NW_004955475.1 Reference ChiLan1.0 Primary Assembly

    Range
    9992888..10056197
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005401627.1 → XP_005401684.1  disks large homolog 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C2VZE6
    Conserved Domains (5) summary
    cd12029
    Location:521 → 587
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00071
    Location:680 → 796
    GMPK; Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine ...
    cd00992
    Location:403 → 481
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:677 → 855
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:330 → 404
    PDZ_assoc; PDZ-associated domain of NMDA receptors

  2. XM_005401629.1 → XP_005401686.1  disks large homolog 3 isoform X3

    UniProtKB/TrEMBL
    A0A8C2VYW8, A0A8C2VZE6
    Related
    ENSCLAP00000022696.1, ENSCLAT00000022904.1
    Conserved Domains (5) summary
    cd12029
    Location:521 → 587
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00071
    Location:662 → 778
    GMPK; Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine ...
    cd00992
    Location:403 → 481
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:659 → 837
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:330 → 404
    PDZ_assoc; PDZ-associated domain of NMDA receptors

  3. XM_005401630.1 → XP_005401687.1  disks large homolog 3 isoform X4

    UniProtKB/TrEMBL
    A0A8C2VZE6, A0A8C2YTS1
    Related
    ENSCLAP00000022698.1, ENSCLAT00000022906.1
    Conserved Domains (5) summary
    cd12029
    Location:521 → 587
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00071
    Location:648 → 764
    GMPK; Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine ...
    cd00992
    Location:403 → 481
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:645 → 823
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:330 → 404
    PDZ_assoc; PDZ-associated domain of NMDA receptors

  4. XM_005401628.1 → XP_005401685.1  disks large homolog 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C2VZE6
    Conserved Domains (5) summary
    cd12029
    Location:503 → 569
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00071
    Location:662 → 778
    GMPK; Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine ...
    cd00992
    Location:385 → 463
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:659 → 837
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:312 → 386
    PDZ_assoc; PDZ-associated domain of NMDA receptors

  5. XM_005401631.1 → XP_005401688.1  disks large homolog 3 isoform X5

    UniProtKB/TrEMBL
    A0A8C2VZE6
    Conserved Domains (5) summary
    cd12029
    Location:503 → 569
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00071
    Location:630 → 746
    GMPK; Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine ...
    cd00992
    Location:385 → 463
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:627 → 805
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:312 → 386
    PDZ_assoc; PDZ-associated domain of NMDA receptors

  6. XM_005401632.2 → XP_005401689.1  disks large homolog 3 isoform X6

    UniProtKB/TrEMBL
    A0A8C2VYX4
    Related
    ENSCLAP00000022700.1, ENSCLAT00000022908.1
    Conserved Domains (4) summary
    cd00071
    Location:324 → 440
    GMPK; Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine ...
    cd00992
    Location:47 → 125
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:321 → 499
    Guanylate_kin; Guanylate kinase
    cl17036
    Location:165 → 231
    SH3; Src Homology 3 domain superfamily

  7. XM_005401633.2 → XP_005401690.1  disks large homolog 3 isoform X7

    See identical proteins and their annotated locations for XP_005401690.1

    Conserved Domains (3) summary
    smart00072
    Location:186 → 353
    GuKc; Guanylate kinase homologues
    pfam00625
    Location:175 → 353
    Guanylate_kin; Guanylate kinase
    cl17036
    Location:19 → 85
    SH3; Src Homology 3 domain superfamily
Nucleotide Protein
Heading Accession and Version

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