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Dpyd dihydropyrimidine dehydrogenase [ Chinchilla lanigera (long-tailed chinchilla) ]

Gene ID: 102020281, updated on 10-Mar-2024

Summary

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Gene symbol
Dpyd
Gene description
dihydropyrimidine dehydrogenase
See related
Ensembl:ENSCLAG00000009825
Gene type
protein coding
RefSeq status
MODEL
Organism
Chinchilla lanigera
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Chinchillidae; Chinchilla
Annotation information
Annotation category: partial on reference assembly
Orthologs
human mouse all
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Genomic context

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See Dpyd in Genome Data Viewer
Location:
chromosome: Un
Exon count:
23
Annotation release Status Assembly Chr Location
101 current ChiLan1.0 (GCF_000276665.1) Unplaced Scaffold NW_004955435.1 (2007185..2800907, complement)

NW_004955435.1Genomic Context describing neighboring genes Neighboring gene peptidyl-prolyl cis-trans isomerase H pseudogene Neighboring gene polypyrimidine tract binding protein 2 Neighboring gene nucleophosmin-like Neighboring gene uncharacterized LOC102028790 Neighboring gene sorting nexin 7

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004955435.1 Unplaced Scaffold Reference ChiLan1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NADP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables dihydropyrimidine dehydrogenase (NADP+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables uracil binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in thymine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in uracil catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dihydropyrimidine dehydrogenase [NADP(+)]

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Chinchilla lanigera Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ChiLan1.0 Primary Assembly

Genomic

  1. NW_004955435.1 Reference ChiLan1.0 Primary Assembly

    Range
    2007185..2800907 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005389092.1 → XP_005389149.1  dihydropyrimidine dehydrogenase [NADP(+)]

    UniProtKB/TrEMBL
    A0A8C2VI07
    Related
    ENSCLAP00000014238.1, ENSCLAT00000014396.1
    Conserved Domains (7) summary
    PRK08318
    Location:562 → 1037
    PRK08318; dihydropyrimidine dehydrogenase subunit B; Validated
    PRK11749
    Location:88 → 543
    PRK11749; dihydropyrimidine dehydrogenase subunit A; Provisional
    cd02940
    Location:562 → 864
    DHPD_FMN; Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain. DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and ...
    pfam13187
    Location:983 → 1027
    Fer4_9; 4Fe-4S dicluster domain
    pfam13450
    Location:224 → 268
    NAD_binding_8; NAD(P)-binding Rossmann-like domain
    pfam14691
    Location:86 → 198
    Fer4_20; Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
    cl19102
    Location:1007 → 1053
    Fer4_8; 4Fe-4S dicluster domain
Nucleotide Protein
Heading Accession and Version

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