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KCNAB1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 [ Macaca fascicularis (crab-eating macaque) ]

Gene ID: 101866714, updated on 8-Jun-2024

Summary

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Gene symbol
KCNAB1
Gene description
potassium voltage-gated channel subfamily A regulatory beta subunit 1
See related
Ensembl:ENSMFAG00000032077
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca fascicularis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_05 current T2T-MFA8v1.0 (GCF_037993035.1) 2 NC_088376.1 (59009113..59505996)
102 previous assembly MFA1912RKSv2 (GCF_012559485.2) 2 NC_052256.1 (135254840..135751925, complement)

Chromosome 2 - NC_088376.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U3 Neighboring gene vomeronasal type-2 receptor 1-like Neighboring gene double-strand break repair protein MRE11-like Neighboring gene U5 small nuclear ribonucleoprotein 40 kDa protein-like Neighboring gene signal sequence receptor subunit 3 Neighboring gene uncharacterized LOC102123344 Neighboring gene TCDD inducible poly(ADP-ribose) polymerase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Rate of evolution in brain-expressed genes in humans and other primates. Wang HY, et al. PLoS Biol, 2007 Feb. PMID 17194215, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aldo-keto reductase (NADPH) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables potassium channel regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane transporter binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables voltage-gated potassium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of delayed rectifier potassium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in potassium ion transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extrinsic component of cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in juxtaparanode region of axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of voltage-gated potassium channel complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
voltage-gated potassium channel subunit beta-1
Names
potassium voltage-gated channel subfamily A member regulatory beta subunit 1
XP_005546232.1
XP_005546234.1
XP_005546235.1
XP_045242663.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_037993035.1-RS_2024_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MFA8v1.0

Genomic

  1. NC_088376.1 Reference T2T-MFA8v1.0

    Range
    59009113..59505996
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_045386728.2 → XP_045242663.1  voltage-gated potassium channel subunit beta-1 isoform X4

    UniProtKB/TrEMBL
    A0A2K5V0I1
    Conserved Domains (1) summary
    cl00470
    Location:3 → 322
    AKR_SF; Aldo-keto reductase (AKR) superfamily

  2. XM_005546175.4 → XP_005546232.1  voltage-gated potassium channel subunit beta-1 isoform X1

    See identical proteins and their annotated locations for XP_005546232.1

    UniProtKB/TrEMBL
    A0A2K5V0E9
    Related
    ENSMFAP00000018200.1
    Conserved Domains (1) summary
    cd19159
    Location:89 → 411
    AKR_KCAB1B_AKR6A3-like; voltage-gated potassium channel subunit beta-1 (KCAB1B) and similar proteins

  3. XM_005546177.4 → XP_005546234.1  voltage-gated potassium channel subunit beta-1 isoform X2

    See identical proteins and their annotated locations for XP_005546234.1

    UniProtKB/TrEMBL
    A0A2K5V0F2, G7NZK2
    Related
    ENSMFAP00000018205.1
    Conserved Domains (1) summary
    cd19159
    Location:78 → 400
    AKR_KCAB1B_AKR6A3-like; voltage-gated potassium channel subunit beta-1 (KCAB1B) and similar proteins

  4. XM_005546178.4 → XP_005546235.1  voltage-gated potassium channel subunit beta-1 isoform X3

    See identical proteins and their annotated locations for XP_005546235.1

    UniProtKB/TrEMBL
    A0A2K5V0K6, G7NZK2
    Related
    ENSMFAP00000018208.1
    Conserved Domains (1) summary
    cd19159
    Location:71 → 393
    AKR_KCAB1B_AKR6A3-like; voltage-gated potassium channel subunit beta-1 (KCAB1B) and similar proteins

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001285115.1: Suppressed sequence

    Description
    NM_001285115.1: This RefSeq record was removed as a result of standard genome annotation processing. Contact info@ncbi.nlm.nih.gov for further information.
Nucleotide Protein
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