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Ncf2 neutrophil cytosolic factor 2 [ Mesocricetus auratus (golden hamster) ]

Gene ID: 101829248, updated on 8-Mar-2024

Summary

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Gene symbol
Ncf2
Gene description
neutrophil cytosolic factor 2
See related
EnsemblRapid:ENSMAUG00000020211
Gene type
protein coding
RefSeq status
MODEL
Organism
Mesocricetus auratus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Mesocricetus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
103 current BCM_Maur_2.0 (GCF_017639785.1) Unplaced Scaffold NW_024429266.1 (38389170..38418224, complement)
102 previous assembly MesAur1.0 (GCF_000349665.1) Unplaced Scaffold NW_004801631.1 (1918790..1947935)

NW_024429266.1Genomic Context describing neighboring genes Neighboring gene 28S ribosomal protein S36, mitochondrial Neighboring gene SMG7 nonsense mediated mRNA decay factor Neighboring gene 60S ribosomal protein L4-like Neighboring gene ATP synthase subunit g, mitochondrial-like Neighboring gene actin related protein 2/3 complex subunit 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. De novo assembly, annotation, and characterization of the whole brain transcriptome of male and female Syrian hamsters. McCann KE, et al. Sci Rep, 2017 Jan 10. PMID 28071753, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables superoxide-generating NADPH oxidase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in phagocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in respiratory burst IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in superoxide anion generation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of NADPH oxidase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
neutrophil cytosol factor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mesocricetus auratus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference BCM_Maur_2.0 Primary Assembly

Genomic

  1. NW_024429266.1 Reference BCM_Maur_2.0 Primary Assembly

    Range
    38389170..38418224 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005071285.4 → XP_005071342.1  neutrophil cytosol factor 2

    UniProtKB/TrEMBL
    A0A1U7QFQ4
    Related
    ENSMAUP00000022926.2, ENSMAUT00000026930.2
    Conserved Domains (6) summary
    cd06406
    Location:351 → 429
    PB1_P67; A PB1 domain is present in p67 proteins which forms a signaling complex with p40, a crucial step for activation of NADPH oxidase during phagocytosis. PB1 domain is a modular domain mediating specific protein-protein interactions which play a role in ...
    cd11871
    Location:244 → 297
    SH3_p67phox_N; N-terminal (or first) Src Homology 3 domain of the p67phox subunit of NADPH oxidase
    cd12046
    Location:461 → 513
    SH3_p67phox_C; C-terminal (or second) Src Homology 3 domain of the p67phox subunit of NADPH oxidase
    sd00006
    Location:6 → 32
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:71 → 98
    TPR_1; Tetratricopeptide repeat
    pfam13424
    Location:38 → 102
    TPR_12; Tetratricopeptide repeat
Nucleotide Protein
Heading Accession and Version

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