U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ACTN2 actinin alpha 2 [ Anas platyrhynchos (mallard) ]

Gene ID: 101791061, updated on 8-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
ACTN2
Gene description
actinin alpha 2
Locus tag
Anapl_08531
See related
EnsemblRapid:ENSAPLG00030005459
Gene type
protein coding
RefSeq status
MODEL
Organism
Anas platyrhynchos
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae; Anatinae; Anas
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 3
Exon count:
21
Annotation release Status Assembly Chr Location
104 current ZJU1.0 (GCF_015476345.1) 3 NC_051774.1 (25848972..25916741)
103 previous assembly IASCAAS_PekingDuck_PBH1.5 (GCF_003850225.1) 3 NC_040048.1 (24842024..24911271)

Chromosome 3 - NC_051774.1Genomic Context describing neighboring genes Neighboring gene HEAT repeat containing 1 Neighboring gene uncharacterized LOC106018338 Neighboring gene 5-methyltetrahydrofolate-homocysteine methyltransferase Neighboring gene uncharacterized LOC106018337

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in muscle cell development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Z disc IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cortical actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
alpha-actinin-2
Names
Alpha-actinin-2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Anas platyrhynchos Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ZJU1.0 Primary Assembly

Genomic

  1. NC_051774.1 Reference ZJU1.0 Primary Assembly

    Range
    25848972..25916741
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005023594.5 → XP_005023651.1  alpha-actinin-2 isoform X1

    See identical proteins and their annotated locations for XP_005023651.1

    UniProtKB/TrEMBL
    A0A493TCE5, R0JMH7, U3IMG7
    Related
    ENSAPLP00030011125.1, ENSAPLT00030014598.1
    Conserved Domains (6) summary
    COG5126
    Location:753 → 897
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
    cd00176
    Location:405 → 632
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00435
    Location:284 → 394
    Spectrin; Spectrin repeat
    pfam08726
    Location:827 → 893
    EFhand_Ca_insen; Ca2+ insensitive EF hand
    cd21214
    Location:38 → 142
    CH_ACTN_rpt1; first calponin homology (CH) domain found in the alpha-actinin family
    cd21216
    Location:146 → 260
    CH_ACTN_rpt2; second calponin homology (CH) domain found in the alpha-actinin family

  2. XM_038177016.1 → XP_038032944.1  alpha-actinin-2 isoform X2

    UniProtKB/TrEMBL
    U3IMG7
    Related
    ENSAPLP00030011222.1, ENSAPLT00030014734.1
    Conserved Domains (6) summary
    PTZ00184
    Location:750 → 832
    PTZ00184; calmodulin; Provisional
    cd00176
    Location:405 → 632
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00435
    Location:284 → 394
    Spectrin; Spectrin repeat
    pfam08726
    Location:805 → 871
    EFhand_Ca_insen; Ca2+ insensitive EF hand
    cd21214
    Location:38 → 142
    CH_ACTN_rpt1; first calponin homology (CH) domain found in the alpha-actinin family
    cd21216
    Location:146 → 260
    CH_ACTN_rpt2; second calponin homology (CH) domain found in the alpha-actinin family
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.