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Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101723713, updated on 8-Mar-2024

Summary

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Gene symbol
Cacnb4
Gene description
calcium voltage-gated channel auxiliary subunit beta 4
See related
Ensembl:ENSHGLG00000001958
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
17
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624866.1 (4973087..5287477)

NW_004624866.1Genomic Context describing neighboring genes Neighboring gene ubiquitin-associated protein 1 pseudogene Neighboring gene formin like 2 Neighboring gene RNA-binding protein 3 pseudogene Neighboring gene signal transducing adaptor molecule 2 Neighboring gene uncharacterized LOC106008174 Neighboring gene tRNA pseudouridine(38/39) synthase pseudogene Neighboring gene ubiquitin carboxyl-terminal hydrolase 32-like Neighboring gene nucleolar GTP-binding protein 2 pseudogene Neighboring gene ADP ribosylation factor like GTPase 5A Neighboring gene nebulin Neighboring gene tumor protein D52 pseudogene

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624866 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables high voltage-gated calcium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuromuscular junction development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of voltage-gated calcium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of voltage-gated calcium channel complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
voltage-dependent L-type calcium channel subunit beta-4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624866.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    4973087..5287477
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021248409.1 → XP_021104068.1  voltage-dependent L-type calcium channel subunit beta-4 isoform X5

    Conserved Domains (3) summary
    cd12043
    Location:90 → 157
    SH3_CACNB4; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta4
    pfam12052
    Location:49 → 90
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
    cl27059
    Location:173 → 318
    Guanylate_kin; Guanylate kinase

  2. XM_004870022.3 → XP_004870079.1  voltage-dependent L-type calcium channel subunit beta-4 isoform X1

    Related
    ENSHGLP00000002602.1, ENSHGLT00000002654.1
    Conserved Domains (4) summary
    cd12043
    Location:90 → 157
    SH3_CACNB4; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta4
    pfam00625
    Location:217 → 397
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:49 → 90
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
    cl17190
    Location:227 → 398
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

  3. XM_004870023.3 → XP_004870080.1  voltage-dependent L-type calcium channel subunit beta-4 isoform X2

    Conserved Domains (4) summary
    cd12043
    Location:73 → 140
    SH3_CACNB4; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta4
    pfam00625
    Location:200 → 380
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:32 → 73
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
    cl17190
    Location:210 → 381
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

  4. XM_004870024.3 → XP_004870081.1  voltage-dependent L-type calcium channel subunit beta-4 isoform X3

    UniProtKB/TrEMBL
    A0A0P6J645
    Related
    ENSHGLP00000002604.1, ENSHGLT00000002656.1
    Conserved Domains (4) summary
    cd12043
    Location:57 → 124
    SH3_CACNB4; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta4
    pfam00625
    Location:184 → 364
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:16 → 57
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
    cl17190
    Location:194 → 365
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

  5. XM_004870025.3 → XP_004870082.1  voltage-dependent L-type calcium channel subunit beta-4 isoform X4

    Related
    ENSHGLP00000002603.1, ENSHGLT00000002655.1
    Conserved Domains (4) summary
    cd12043
    Location:44 → 111
    SH3_CACNB4; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta4
    pfam00625
    Location:171 → 351
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:3 → 44
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
    cl17190
    Location:181 → 352
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

  6. XM_021248410.1 → XP_021104069.1  voltage-dependent L-type calcium channel subunit beta-4 isoform X6

    Conserved Domains (1) summary
    cl27059
    Location:40 → 220
    Guanylate_kin; Guanylate kinase
Nucleotide Protein
Heading Accession and Version

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