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Arhgef12 Rho guanine nucleotide exchange factor 12 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101716885, updated on 8-Mar-2024

Summary

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Gene symbol
Arhgef12
Gene description
Rho guanine nucleotide exchange factor 12
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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See Arhgef12 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624784.1 (15693044..15784171)

NW_004624784.1Genomic Context describing neighboring genes Neighboring gene serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform pseudogene Neighboring gene TLC domain containing 5

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624784 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho guanine nucleotide exchange factor 12

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624784.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    15693044..15784171
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004856815.3 → XP_004856872.1  rho guanine nucleotide exchange factor 12 isoform X1

    UniProtKB/TrEMBL
    G5BHQ4
    Conserved Domains (2) summary
    cd00992
    Location:71 → 145
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam05615
    Location:204 → 256
    THOC7; Tho complex subunit 7

  2. XM_021237798.1 → XP_021093457.1  rho guanine nucleotide exchange factor 12 isoform X3

    UniProtKB/TrEMBL
    G5BHQ4
    Conserved Domains (2) summary
    cd00992
    Location:48 → 93
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam05615
    Location:152 → 204
    THOC7; Tho complex subunit 7

  3. XM_021237797.1 → XP_021093456.1  rho guanine nucleotide exchange factor 12 isoform X2

    UniProtKB/TrEMBL
    G5BHQ4
    Conserved Domains (2) summary
    cd00992
    Location:52 → 126
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam05615
    Location:185 → 237
    THOC7; Tho complex subunit 7
Nucleotide Protein
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