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TLL2 tolloid like 2 [ Echinops telfairi (small Madagascar hedgehog) ]

Gene ID: 101655845, updated on 8-Mar-2024

Summary

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Gene symbol
TLL2
Gene description
tolloid like 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Echinops telfairi
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Tenrecidae; Tenrecinae; Echinops
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
23
Annotation release Status Assembly Chr Location
103 current ASM31398v2 (GCF_000313985.2) Unplaced Scaffold NW_022103968.1 (32222023..32391184)
101 previous assembly EchTel2.0 (GCF_000313985.1) Unplaced Scaffold NW_004558709.1 (31932373..32100243)

NW_022103968.1Genomic Context describing neighboring genes Neighboring gene phosphoinositide-3-kinase adaptor protein 1 Neighboring gene guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Neighboring gene transmembrane 9 superfamily member 3 Neighboring gene oligodendrocytic myelin paranodal and inner loop protein Neighboring gene DNA nucleotidylexotransferase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tolloid-like protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Echinops telfairi Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM31398v2 Primary Assembly

Genomic

  1. NW_022103968.1 Reference ASM31398v2 Primary Assembly

    Range
    32222023..32391184
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013004185.2 → XP_012859639.1  tolloid-like protein 2

    Conserved Domains (3) summary
    cd04281
    Location:204 → 403
    ZnMc_BMP1_TLD; Zinc-dependent metalloprotease; BMP1/TLD-like subfamily. BMP1 (Bone morphogenetic protein 1) and TLD (tolloid)-like metalloproteases play vital roles in extracellular matrix formation, by cleaving precursor proteins such as enzymes, structural proteins, ...
    pfam00431
    Location:518 → 627
    CUB; CUB domain
    pfam14670
    Location:790 → 825
    FXa_inhibition; Coagulation Factor Xa inhibitory site
Nucleotide Protein
Heading Accession and Version

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