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PFAS phosphoribosylformylglycinamidine synthase [ Condylura cristata (star-nosed mole) ]

Gene ID: 101627028, updated on 8-Mar-2024

Summary

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Gene symbol
PFAS
Gene description
phosphoribosylformylglycinamidine synthase
Gene type
protein coding
RefSeq status
MODEL
Organism
Condylura cristata
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Eulipotyphla; Talpidae; Condylura
Orthologs
human mouse all
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Genomic context

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See PFAS in Genome Data Viewer
Location:
chromosome: Un
Exon count:
28
Annotation release Status Assembly Chr Location
101 current ConCri1.0 (GCF_000260355.1) Unplaced Scaffold NW_004567118.1 (28544124..28563525, complement)

NW_004567118.1Genomic Context describing neighboring genes Neighboring gene Rho guanine nucleotide exchange factor 15 Neighboring gene solute carrier family 25 member 35 Neighboring gene RAN guanine nucleotide release factor Neighboring gene CST telomere replication complex component 1 Neighboring gene transfer RNA proline (anticodon CGG)

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004567118.1 Unplaced Scaffold Reference ConCri1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphoribosylformylglycinamidine synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in 'de novo' IMP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphoribosylformylglycinamidine synthase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Condylura cristata Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ConCri1.0

Genomic

  1. NW_004567118.1 Reference ConCri1.0

    Range
    28544124..28563525 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012726574.1 → XP_012582028.1  phosphoribosylformylglycinamidine synthase isoform X2

    Conserved Domains (4) summary
    cd02204
    Location:672 → 946
    PurL_repeat2; PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP, ...
    TIGR01735
    Location:15 → 1298
    FGAM_synt; phosphoribosylformylglycinamidine synthase, single chain form
    pfam13507
    Location:1028 → 1298
    GATase_5; CobB/CobQ-like glutamine amidotransferase domain
    cl10019
    Location:226 → 573
    PurM-like; AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain ...

  2. XM_004684613.2 → XP_004684670.2  phosphoribosylformylglycinamidine synthase isoform X1

    Conserved Domains (4) summary
    cd02203
    Location:226 → 616
    PurL_repeat1; PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP, ...
    cd02204
    Location:715 → 989
    PurL_repeat2; PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP, ...
    TIGR01735
    Location:15 → 1341
    FGAM_synt; phosphoribosylformylglycinamidine synthase, single chain form
    pfam13507
    Location:1071 → 1341
    GATase_5; CobB/CobQ-like glutamine amidotransferase domain
Nucleotide Protein
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