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cdc42bpb CDC42 binding protein kinase beta (DMPK-like) [ Maylandia zebra (zebra mbuna) ]

Gene ID: 101479053, updated on 8-Mar-2024

Summary

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Gene symbol
cdc42bpb
Gene description
CDC42 binding protein kinase beta (DMPK-like)
See related
Ensembl:ENSMZEG00005015072
Gene type
protein coding
RefSeq status
MODEL
Organism
Maylandia zebra
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids; Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex
Orthologs
human zebrafish all
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Genomic context

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See cdc42bpb in Genome Data Viewer
Location:
chromosome: LG15
Exon count:
38
Annotation release Status Assembly LG Location
104 current M_zebra_UMD2a (GCF_000238955.4) LG15 NC_036794.1 (23761826..23788674, complement)
101 previous assembly MetZeb1.1 (GCF_000238955.1) Unplaced Scaffold NW_004531948.1 (503712..531387)

Linkage Group LG15 - NC_036794.1Genomic Context describing neighboring genes Neighboring gene VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog Neighboring gene G protein-coupled receptor 132b Neighboring gene uncharacterized LOC112436040 Neighboring gene NACHT, LRR and PYD domains-containing protein 12-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actomyosin structure organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-threonine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase MRCK beta

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Maylandia zebra Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference M_zebra_UMD2a Primary Assembly

Genomic

  1. NC_036794.1 Reference M_zebra_UMD2a Primary Assembly

    Range
    23761826..23788674 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004573148.5 → XP_004573205.1  serine/threonine-protein kinase MRCK beta

    UniProtKB/TrEMBL
    A0A3P9CCV0, A0A3P9CD27
    Related
    ENSMZEP00005020183.1, ENSMZET00005020834.1
    Conserved Domains (8) summary
    pfam08826
    Location:888 → 948
    DMPK_coil; DMPK coiled coil domain like
    smart00220
    Location:74 → 340
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    COG1340
    Location:471 → 765
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    cd00029
    Location:1029 → 1078
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd01243
    Location:1088 → 1222
    PH_MRCK; MRCK (myotonic dystrophy-related Cdc42-binding kinase) pleckstrin homology (PH) domain
    pfam00780
    Location:1248 → 1513
    CNH; CNH domain
    pfam15796
    Location:517 → 595
    KELK; KELK-motif containing domain of MRCK Ser/Thr protein kinase
    cl21453
    Location:17 → 409
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
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