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LLGL2 LLGL scribble cell polarity complex component 2 [ Odobenus rosmarus divergens (Pacific walrus) ]

Gene ID: 101385653, updated on 8-Mar-2024

Summary

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Gene symbol
LLGL2
Gene description
LLGL scribble cell polarity complex component 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Odobenus rosmarus divergens (sub-species: divergens)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae; Odobenus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
25
Annotation release Status Assembly Chr Location
101 current Oros_1.0 (GCF_000321225.1) Unplaced Scaffold NW_004450293.1 (2245638..2278423, complement)

NW_004450293.1Genomic Context describing neighboring genes Neighboring gene RecQ like helicase 5 Neighboring gene small integral membrane protein 5 Neighboring gene unconventional myosin-XVB-like Neighboring gene proline-rich protein 2-like Neighboring gene tRNA splicing endonuclease subunit 54 Neighboring gene CASK interacting protein 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004450293.1 Unplaced Scaffold Reference Oros_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables myosin II binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cortical actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of spindle orientation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of establishment or maintenance of cell polarity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of protein secretion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cortical actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
lethal(2) giant larvae protein homolog 2
Names
LLGL2, scribble cell polarity complex component

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Odobenus rosmarus divergens Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Oros_1.0 Primary Assembly

Genomic

  1. NW_004450293.1 Reference Oros_1.0 Primary Assembly

    Range
    2245638..2278423 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012560250.1 → XP_012415704.1  lethal(2) giant larvae protein homolog 2

    UniProtKB/TrEMBL
    A0A9B0G7N9
    Conserved Domains (4) summary
    COG2319
    Location:73 → 454
    WD40; WD40 repeat [General function prediction only]
    pfam08366
    Location:273 → 371
    LLGL; LLGL2
    sd00039
    Location:76 → 113
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:47 → 261
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein
Heading Accession and Version

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