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FGFR3 fibroblast growth factor receptor 3 [ Odobenus rosmarus divergens (Pacific walrus) ]

Gene ID: 101381434, updated on 8-Mar-2024

Summary

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Gene symbol
FGFR3
Gene description
fibroblast growth factor receptor 3
Gene type
protein coding
RefSeq status
MODEL
Organism
Odobenus rosmarus divergens (sub-species: divergens)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae; Odobenus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
18
Annotation release Status Assembly Chr Location
101 current Oros_1.0 (GCF_000321225.1) Unplaced Scaffold NW_004450315.1 (3533798..3548182, complement)

NW_004450315.1Genomic Context describing neighboring genes Neighboring gene nuclear receptor binding SET domain protein 2 Neighboring gene leucine zipper and EF-hand containing transmembrane protein 1 Neighboring gene transforming acidic coiled-coil containing protein 3 Neighboring gene transmembrane protein 129, E3 ubiquitin ligase

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004450315.1 Unplaced Scaffold Reference Oros_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fibroblast growth factor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fibroblast growth factor receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fibroblast growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
fibroblast growth factor receptor 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Odobenus rosmarus divergens Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Oros_1.0 Primary Assembly

Genomic

  1. NW_004450315.1 Reference Oros_1.0 Primary Assembly

    Range
    3533798..3548182 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012560920.1 → XP_012416374.1  fibroblast growth factor receptor 3 isoform X3

    Conserved Domains (6) summary
    cd05857
    Location:158 → 242
    Ig2_FGFR; Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor
    cd05858
    Location:265 → 354
    Ig3_FGFR-2; Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor 2 (FGFR2)
    cd05100
    Location:456 → 789
    PTKc_FGFR3; Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 3
    smart00408
    Location:53 → 110
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:257 → 353
    IG_like; Immunoglobulin like
    pfam07714
    Location:469 → 745
    Pkinase_Tyr; Protein tyrosine kinase

  2. XM_004396219.1 → XP_004396276.1  fibroblast growth factor receptor 3 isoform X7

    UniProtKB/TrEMBL
    A0A2U3VML8
    Conserved Domains (6) summary
    cd04974
    Location:268 → 357
    Ig3_FGFR; Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor (FGFR)
    cd05857
    Location:161 → 245
    Ig2_FGFR; Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor
    cd05100
    Location:347 → 680
    PTKc_FGFR3; Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 3
    smart00408
    Location:53 → 110
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:171 → 245
    IG_like; Immunoglobulin like
    pfam07714
    Location:360 → 636
    Pkinase_Tyr; Protein tyrosine kinase

  3. XM_004396218.1 → XP_004396275.1  fibroblast growth factor receptor 3 isoform X2

    UniProtKB/TrEMBL
    A0A2U3VMX1
    Conserved Domains (6) summary
    cd05857
    Location:161 → 245
    Ig2_FGFR; Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor
    cd05858
    Location:268 → 357
    Ig3_FGFR-2; Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor 2 (FGFR2)
    cd05100
    Location:459 → 792
    PTKc_FGFR3; Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 3
    smart00408
    Location:53 → 110
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:260 → 356
    IG_like; Immunoglobulin like
    pfam07714
    Location:472 → 748
    Pkinase_Tyr; Protein tyrosine kinase

  4. XM_004396217.1 → XP_004396274.1  fibroblast growth factor receptor 3 isoform X1

    UniProtKB/TrEMBL
    A0A2U3VMK7
    Conserved Domains (6) summary
    cd04974
    Location:268 → 356
    Ig3_FGFR; Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor (FGFR)
    cd05857
    Location:161 → 245
    Ig2_FGFR; Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor
    cd05100
    Location:461 → 794
    PTKc_FGFR3; Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 3
    smart00408
    Location:53 → 110
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:260 → 355
    IG_like; Immunoglobulin like
    pfam07714
    Location:474 → 750
    Pkinase_Tyr; Protein tyrosine kinase

  5. XM_012560923.1 → XP_012416377.1  fibroblast growth factor receptor 3 isoform X6

    Conserved Domains (6) summary
    cd05857
    Location:113 → 197
    Ig2_FGFR; Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor
    cd05858
    Location:220 → 309
    Ig3_FGFR-2; Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor 2 (FGFR2)
    cd05100
    Location:411 → 744
    PTKc_FGFR3; Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 3
    smart00408
    Location:27 → 84
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:212 → 308
    IG_like; Immunoglobulin like
    pfam07714
    Location:424 → 700
    Pkinase_Tyr; Protein tyrosine kinase

  6. XM_012560922.1 → XP_012416376.1  fibroblast growth factor receptor 3 isoform X5

    Conserved Domains (6) summary
    cd05857
    Location:131 → 215
    Ig2_FGFR; Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor
    cd05858
    Location:238 → 327
    Ig3_FGFR-2; Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor 2 (FGFR2)
    cd05100
    Location:429 → 762
    PTKc_FGFR3; Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 3
    smart00408
    Location:27 → 84
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:230 → 326
    IG_like; Immunoglobulin like
    pfam07714
    Location:442 → 718
    Pkinase_Tyr; Protein tyrosine kinase

  7. XM_012560921.1 → XP_012416375.1  fibroblast growth factor receptor 3 isoform X4

    Conserved Domains (6) summary
    cd05857
    Location:131 → 215
    Ig2_FGFR; Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor
    cd05858
    Location:238 → 327
    Ig3_FGFR-2; Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor 2 (FGFR2)
    cd05100
    Location:430 → 763
    PTKc_FGFR3; Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 3
    smart00408
    Location:27 → 84
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:230 → 326
    IG_like; Immunoglobulin like
    pfam07714
    Location:443 → 719
    Pkinase_Tyr; Protein tyrosine kinase
Nucleotide Protein
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