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ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit [ Trichechus manatus latirostris (Florida manatee) ]

Gene ID: 101354098, updated on 8-Mar-2024

Summary

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Gene symbol
ERCC2
Gene description
ERCC excision repair 2, TFIIH core complex helicase subunit
See related
EnsemblRapid:ENSTMLG00000010025
Gene type
protein coding
RefSeq status
MODEL
Organism
Trichechus manatus latirostris (sub-species: latirostris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus
Orthologs
human mouse all
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Genomic context

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See ERCC2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_01 current TriManLat1.0 (GCF_000243295.1) Unplaced Scaffold NW_004444023.1 (183558..201516, complement)

NW_004444023.1Genomic Context describing neighboring genes Neighboring gene creatine kinase, M-type Neighboring gene kinesin light chain 3 Neighboring gene protein phosphatase 1 regulatory subunit 13 like Neighboring gene RNA polymerase I subunit G

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004444023 Unplaced Scaffold Reference TriManLat1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables damaged DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in nucleotide-excision repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of mitotic recombination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
general transcription and DNA repair factor IIH helicase subunit XPD
Names
excision repair cross-complementing rodent repair deficiency, complementation group 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000243295.1-RS_2024_01

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference TriManLat1.0 Primary Assembly

Genomic

  1. NW_004444023.1 Reference TriManLat1.0 Primary Assembly

    Range
    183558..201516 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004381574.2 → XP_004381631.1  general transcription and DNA repair factor IIH helicase subunit XPD

    UniProtKB/TrEMBL
    A0A2Y9DW80
    Related
    ENSTMLP00000014173.1, ENSTMLT00000015212.1
    Conserved Domains (4) summary
    smart00488
    Location:1 → 256
    DEXDc2; DEAD-like helicases superfamily
    smart00491
    Location:518 → 662
    HELICc2; helicase superfamily c-terminal domain
    TIGR00604
    Location:1 → 684
    rad3; DNA repair helicase (rad3)
    pfam06777
    Location:245 → 389
    HBB; Helical and beta-bridge domain
Nucleotide Protein
Heading Accession and Version

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