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ITPR2 inositol 1,4,5-trisphosphate receptor type 2 [ Gorilla gorilla gorilla (western lowland gorilla) ]

Gene ID: 101151502, updated on 6-Jun-2024

Summary

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Gene symbol
ITPR2
Gene description
inositol 1,4,5-trisphosphate receptor type 2
See related
Ensembl:ENSGGOG00000008010
Gene type
protein coding
RefSeq status
MODEL
Organism
Gorilla gorilla gorilla (sub-species: gorilla)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Gorilla
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
58
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mGorGor1-v2.0_pri (GCF_029281585.2) 10 NC_073234.2 (74451602..74950902)
RS_2023_04 previous assembly NHGRI_mGorGor1-v1.1-0.2.freeze_pri (GCF_029281585.1) 12 NC_073236.1 (74177347..74676723)

Chromosome 10 - NC_073234.2Genomic Context describing neighboring genes Neighboring gene transmembrane 7 superfamily member 3 Neighboring gene FGFR1 oncogene partner 2 Neighboring gene integrator complex subunit 13 Neighboring gene enoyl-CoA hydratase domain-containing protein 2, mitochondrial-like Neighboring gene uncharacterized LOC129525849 Neighboring gene sarcospan Neighboring gene basic helix-loop-helix family member e41

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables inositol 1,4,5 trisphosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables inositol 1,4,5-trisphosphate-gated calcium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
inositol 1,4,5-trisphosphate receptor type 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029281585.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

Genomic

  1. NC_073234.2 Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

    Range
    74451602..74950902
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031000671.3 → XP_030856531.1  inositol 1,4,5-trisphosphate receptor type 2 isoform X1

    UniProtKB/TrEMBL
    G3QYE0
    Conserved Domains (5) summary
    pfam00520
    Location:2290 → 2552
    Ion_trans; Ion transport protein
    pfam01365
    Location:473 → 670
    RYDR_ITPR; RIH domain
    pfam02815
    Location:232 → 432
    MIR; MIR domain
    pfam08454
    Location:1917 → 2022
    RIH_assoc; RyR and IP3R Homology associated
    pfam08709
    Location:4 → 225
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

  2. XM_055358014.1 → XP_055213989.1  inositol 1,4,5-trisphosphate receptor type 2 isoform X2

    UniProtKB/TrEMBL
    G3QYE0
Nucleotide Protein
Heading Accession and Version

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