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PSEN1 presenilin 1 [ Gorilla gorilla gorilla (western lowland gorilla) ]

Gene ID: 101137687, updated on 6-Jun-2024

Summary

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Gene symbol
PSEN1
Gene description
presenilin 1
See related
Ensembl:ENSGGOG00000002132
Gene type
protein coding
RefSeq status
MODEL
Organism
Gorilla gorilla gorilla (sub-species: gorilla)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Gorilla
Orthologs
human mouse all
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Genomic context

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See PSEN1 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mGorGor1-v2.0_pri (GCF_029281585.2) 15 NC_073239.2 (90016126..90096860)
RS_2023_04 previous assembly NHGRI_mGorGor1-v1.1-0.2.freeze_pri (GCF_029281585.1) 14 NC_073238.1 (81778720..81859430)

Chromosome 15 - NC_073239.2Genomic Context describing neighboring genes Neighboring gene zinc finger FYVE-type containing 1 Neighboring gene required for meiotic nuclear division protein 1 homolog Neighboring gene RNA binding motif protein 25 Neighboring gene U7 small nuclear RNA Neighboring gene U6 spliceosomal RNA Neighboring gene papilin, proteoglycan like sulfated glycoprotein Neighboring gene NUMB endocytic adaptor protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aspartic endopeptidase activity, intramembrane cleaving IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables beta-catenin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cadherin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in amyloid precursor protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in smooth endoplasmic reticulum calcium ion homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
presenilin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029281585.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

Genomic

  1. NC_073239.2 Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

    Range
    90016126..90096860
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031001701.3 → XP_030857561.2  presenilin-1 isoform X2

    UniProtKB/TrEMBL
    G3QI95

  2. XM_031001698.3 → XP_030857558.2  presenilin-1 isoform X1

    UniProtKB/TrEMBL
    G3QI95

  3. XM_031001702.3 → XP_030857562.2  presenilin-1 isoform X2

    UniProtKB/TrEMBL
    G3QI95

  4. XM_031001699.3 → XP_030857559.2  presenilin-1 isoform X1

    UniProtKB/TrEMBL
    G3QI95

  5. XM_063697964.1 → XP_063554034.1  presenilin-1 isoform X1

    UniProtKB/TrEMBL
    G3QI95

  6. XM_063697965.1 → XP_063554035.1  presenilin-1 isoform X2

    UniProtKB/TrEMBL
    G3QI95

  7. XM_055360830.2 → XP_055216805.2  presenilin-1 isoform X1

    UniProtKB/TrEMBL
    G3QI95

  8. XM_055360831.2 → XP_055216806.2  presenilin-1 isoform X2

    UniProtKB/TrEMBL
    G3QI95

  9. XM_031001703.3 → XP_030857563.2  presenilin-1 isoform X3

Nucleotide Protein
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Gene LinkOut

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