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PALS1 protein associated with LIN7 1, MAGUK p55 family member [ Ovis aries (sheep) ]

Gene ID: 101113152, updated on 8-Mar-2024

Summary

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Gene symbol
PALS1
Gene description
protein associated with LIN7 1, MAGUK p55 family member
See related
EnsemblRapid:ENSOARG00020018651
Gene type
protein coding
RefSeq status
MODEL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Also known as
MPP5
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 7
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 7 NC_056060.1 (77221711..77299725)

Chromosome 7 - NC_056060.1Genomic Context describing neighboring genes Neighboring gene gephyrin Neighboring gene mitochondrial import inner membrane translocase subunit Tim8 A-like Neighboring gene golgi associated RAB2 interactor family member 2 Neighboring gene ATPase H+ transporting V1 subunit D Neighboring gene eukaryotic translation initiation factor 2 subunit alpha

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056060.1 Chromosome 7 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in establishment or maintenance of epithelial cell apical/basal polarity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment or maintenance of polarity of embryonic epithelium IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in generation of neurons IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in morphogenesis of an epithelial sheet IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in adherens junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein PALS1
Names
membrane palmitoylated protein 5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
protein associated with LIN7 1, MAGUK family member

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056060.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    77221711..77299725
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042252640.2 → XP_042108574.1  protein PALS1 isoform X1

    UniProtKB/TrEMBL
    A0A6P7EBY9, W5QJ48
    Conserved Domains (5) summary
    smart00569
    Location:189 → 237
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12036
    Location:349 → 411
    SH3_MPP5; Src Homology 3 domain of Membrane Protein, Palmitoylated 5 (or MAGUK p55 subfamily member 5)
    smart00072
    Location:491 → 661
    GuKc; Guanylate kinase homologues
    cd00992
    Location:254 → 333
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam09060
    Location:123 → 170
    L27_N

  2. XM_042252641.2 → XP_042108575.1  protein PALS1 isoform X2

    Conserved Domains (5) summary
    smart00569
    Location:155 → 203
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12036
    Location:315 → 377
    SH3_MPP5; Src Homology 3 domain of Membrane Protein, Palmitoylated 5 (or MAGUK p55 subfamily member 5)
    smart00072
    Location:457 → 627
    GuKc; Guanylate kinase homologues
    cd00992
    Location:220 → 299
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam09060
    Location:89 → 136
    L27_N

  3. XM_027971935.3 → XP_027827736.1  protein PALS1 isoform X1

    UniProtKB/TrEMBL
    A0A6P7EBY9, W5QJ48
    Related
    ENSOARP00020023789.1, ENSOART00020028706.2
    Conserved Domains (5) summary
    smart00569
    Location:189 → 237
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12036
    Location:349 → 411
    SH3_MPP5; Src Homology 3 domain of Membrane Protein, Palmitoylated 5 (or MAGUK p55 subfamily member 5)
    smart00072
    Location:491 → 661
    GuKc; Guanylate kinase homologues
    cd00992
    Location:254 → 333
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam09060
    Location:123 → 170
    L27_N

  4. XM_027971936.3 → XP_027827737.1  protein PALS1 isoform X2

    Conserved Domains (5) summary
    smart00569
    Location:155 → 203
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12036
    Location:315 → 377
    SH3_MPP5; Src Homology 3 domain of Membrane Protein, Palmitoylated 5 (or MAGUK p55 subfamily member 5)
    smart00072
    Location:457 → 627
    GuKc; Guanylate kinase homologues
    cd00992
    Location:220 → 299
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam09060
    Location:89 → 136
    L27_N
Nucleotide Protein Strain
Heading Accession and Version

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