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ptpn13 protein tyrosine phosphatase non-receptor type 13 [ Takifugu rubripes (torafugu) ]

Gene ID: 101077102, updated on 8-Mar-2024

Summary

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Gene symbol
ptpn13
Gene description
protein tyrosine phosphatase non-receptor type 13
See related
Ensembl:ENSTRUG00000013202
Gene type
protein coding
RefSeq status
MODEL
Organism
Takifugu rubripes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: 6
Exon count:
50
Annotation release Status Assembly Chr Location
103 current fTakRub1.2 (GCF_901000725.2) 6 NC_042290.1 (5737950..5766830)
101 previous assembly FUGU5 (GCF_000180615.1) 6 NC_018895.1 (3774996..3803887)

Chromosome 6 - NC_042290.1Genomic Context describing neighboring genes Neighboring gene Rho GTPase activating protein 24 Neighboring gene mitogen-activated protein kinase 10 Neighboring gene SDA1 domain containing 1 Neighboring gene kelch-like family member 8

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphatidylinositol 3-kinase regulatory subunit binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in peptidyl-tyrosine dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein phosphatase non-receptor type 13

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Takifugu rubripes Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fTakRub1.2 Primary Assembly

Genomic

  1. NC_042290.1 Reference fTakRub1.2 Primary Assembly

    Range
    5737950..5766830
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011604592.2 → XP_011602894.2  tyrosine-protein phosphatase non-receptor type 13 isoform X1

    UniProtKB/TrEMBL
    A0A674MU07
    Conserved Domains (8) summary
    smart00228
    Location:1506 → 1596
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    smart00295
    Location:588 → 792
    B41; Band 4.1 homologues
    cd00992
    Location:1109 → 1193
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd13187
    Location:788 → 888
    FERM_C_PTPH13; FERM domain C-lobe of Protein tyrosine phosphatase non-receptor 13 (PTPH13)
    cd17195
    Location:583 → 677
    FERM_F1_PTPN13; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in tyrosine-protein phosphatase non-receptor type 13 (PTPN13)
    pfam16599
    Location:1195 → 1373
    PTN13_u3; Unstructured linker region on PTN13 protein between PDZ
    cl21453
    Location:3 → 177
    PKc_like; Protein Kinases, catalytic domain
    cl28904
    Location:2287 → 2520
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  2. XM_011604593.2 → XP_011602895.2  tyrosine-protein phosphatase non-receptor type 13 isoform X2

    UniProtKB/TrEMBL
    A0A674ML42, A0A674MU07
    Related
    ENSTRUP00000061831.1, ENSTRUT00000067875.1
    Conserved Domains (8) summary
    smart00228
    Location:1506 → 1596
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    smart00295
    Location:588 → 792
    B41; Band 4.1 homologues
    cd00992
    Location:1109 → 1193
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd13187
    Location:788 → 888
    FERM_C_PTPH13; FERM domain C-lobe of Protein tyrosine phosphatase non-receptor 13 (PTPH13)
    cd17195
    Location:583 → 677
    FERM_F1_PTPN13; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in tyrosine-protein phosphatase non-receptor type 13 (PTPN13)
    pfam16599
    Location:1195 → 1373
    PTN13_u3; Unstructured linker region on PTN13 protein between PDZ
    cl21453
    Location:3 → 177
    PKc_like; Protein Kinases, catalytic domain
    cl28904
    Location:2286 → 2519
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  3. XM_011604595.2 → XP_011602897.2  tyrosine-protein phosphatase non-receptor type 13 isoform X4

    UniProtKB/TrEMBL
    A0A674MU07
    Conserved Domains (8) summary
    smart00228
    Location:1501 → 1591
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    smart00295
    Location:588 → 792
    B41; Band 4.1 homologues
    cd00992
    Location:1109 → 1193
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd13187
    Location:788 → 888
    FERM_C_PTPH13; FERM domain C-lobe of Protein tyrosine phosphatase non-receptor 13 (PTPH13)
    cd17195
    Location:583 → 677
    FERM_F1_PTPN13; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in tyrosine-protein phosphatase non-receptor type 13 (PTPN13)
    pfam16599
    Location:1195 → 1373
    PTN13_u3; Unstructured linker region on PTN13 protein between PDZ
    cl21453
    Location:3 → 177
    PKc_like; Protein Kinases, catalytic domain
    cl28904
    Location:2282 → 2515
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  4. XM_011604597.2 → XP_011602899.2  tyrosine-protein phosphatase non-receptor type 13 isoform X7

    UniProtKB/TrEMBL
    A0A674MU07
    Related
    ENSTRUP00000064663.1, ENSTRUT00000063814.1
    Conserved Domains (8) summary
    smart00228
    Location:1501 → 1591
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    smart00295
    Location:588 → 792
    B41; Band 4.1 homologues
    cd00992
    Location:1109 → 1193
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd13187
    Location:788 → 888
    FERM_C_PTPH13; FERM domain C-lobe of Protein tyrosine phosphatase non-receptor 13 (PTPH13)
    cd17195
    Location:583 → 677
    FERM_F1_PTPN13; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in tyrosine-protein phosphatase non-receptor type 13 (PTPN13)
    pfam16599
    Location:1195 → 1373
    PTN13_u3; Unstructured linker region on PTN13 protein between PDZ
    cl21453
    Location:3 → 177
    PKc_like; Protein Kinases, catalytic domain
    cl28904
    Location:2281 → 2514
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  5. XM_011604596.2 → XP_011602898.2  tyrosine-protein phosphatase non-receptor type 13 isoform X5

    UniProtKB/TrEMBL
    A0A674MU07, H2U9H6
    Related
    ENSTRUP00000033592.3, ENSTRUT00000033718.3
    Conserved Domains (8) summary
    smart00228
    Location:1462 → 1552
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    smart00295
    Location:588 → 792
    B41; Band 4.1 homologues
    cd00992
    Location:1109 → 1193
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd13187
    Location:788 → 888
    FERM_C_PTPH13; FERM domain C-lobe of Protein tyrosine phosphatase non-receptor 13 (PTPH13)
    cd17195
    Location:583 → 677
    FERM_F1_PTPN13; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in tyrosine-protein phosphatase non-receptor type 13 (PTPN13)
    pfam16599
    Location:1195 → 1350
    PTN13_u3; Unstructured linker region on PTN13 protein between PDZ
    cl21453
    Location:3 → 177
    PKc_like; Protein Kinases, catalytic domain
    cl28904
    Location:2243 → 2476
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  6. XM_011604594.2 → XP_011602896.2  tyrosine-protein phosphatase non-receptor type 13 isoform X3

    UniProtKB/TrEMBL
    A0A674MU07
    Conserved Domains (8) summary
    smart00228
    Location:1505 → 1595
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    smart00295
    Location:587 → 791
    B41; Band 4.1 homologues
    cd00992
    Location:1108 → 1192
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd13187
    Location:787 → 887
    FERM_C_PTPH13; FERM domain C-lobe of Protein tyrosine phosphatase non-receptor 13 (PTPH13)
    cd17195
    Location:582 → 676
    FERM_F1_PTPN13; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in tyrosine-protein phosphatase non-receptor type 13 (PTPN13)
    pfam16599
    Location:1194 → 1372
    PTN13_u3; Unstructured linker region on PTN13 protein between PDZ
    cl21453
    Location:3 → 177
    PKc_like; Protein Kinases, catalytic domain
    cl28904
    Location:2286 → 2519
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  7. XM_029837879.1 → XP_029693739.1  tyrosine-protein phosphatase non-receptor type 13 isoform X6

    UniProtKB/TrEMBL
    A0A674MU07
    Conserved Domains (7) summary
    smart00228
    Location:1046 → 1136
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    smart00295
    Location:128 → 332
    B41; Band 4.1 homologues
    cd00992
    Location:649 → 733
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd13187
    Location:328 → 428
    FERM_C_PTPH13; FERM domain C-lobe of Protein tyrosine phosphatase non-receptor 13 (PTPH13)
    cd17195
    Location:123 → 217
    FERM_F1_PTPN13; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in tyrosine-protein phosphatase non-receptor type 13 (PTPN13)
    pfam16599
    Location:735 → 913
    PTN13_u3; Unstructured linker region on PTN13 protein between PDZ
    cl28904
    Location:1827 → 2060
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
Nucleotide Protein
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