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ACTN2 actinin alpha 2 [ Saimiri boliviensis (Bolivian squirrel monkey) ]

Gene ID: 101044425, updated on 8-Mar-2024

Summary

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Gene symbol
ACTN2
Gene description
actinin alpha 2
See related
EnsemblRapid:ENSSBOG00000030830
Gene type
protein coding
RefSeq status
MODEL
Organism
Saimiri boliviensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae; Saimiriinae; Saimiri
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
21
Annotation release Status Assembly Chr Location
102 current BCM_Sbol_2.0 (GCF_016699345.1) Unplaced Scaffold NW_024100960.1 (9842516..9920143)

NW_024100960.1Genomic Context describing neighboring genes Neighboring gene EDAR associated via death domain Neighboring gene alpha-enolase-like Neighboring gene galectin 8 Neighboring gene HEAT repeat containing 1 Neighboring gene 5-methyltetrahydrofolate-homocysteine methyltransferase Neighboring gene uncharacterized LOC104652541

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_024100960 Unplaced Scaffold Reference BCM_Sbol_2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in muscle cell development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Z disc IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cortical actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
alpha-actinin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Saimiri boliviensis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference BCM_Sbol_2.0 Primary Assembly

Genomic

  1. NW_024100960.1 Reference BCM_Sbol_2.0 Primary Assembly

    Range
    9842516..9920143
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039464254.1 → XP_039320188.1  alpha-actinin-2

    UniProtKB/TrEMBL
    A0A2K6UAU9
    Related
    ENSSBOP00000029031.2, ENSSBOT00000045912.2
    Conserved Domains (6) summary
    PTZ00184
    Location:747 → 851
    PTZ00184; calmodulin; Provisional
    cd00176
    Location:402 → 629
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00435
    Location:281 → 391
    Spectrin; Spectrin repeat
    pfam08726
    Location:824 → 890
    EFhand_Ca_insen; Ca2+ insensitive EF hand
    cd21214
    Location:35 → 139
    CH_ACTN_rpt1; first calponin homology (CH) domain found in the alpha-actinin family
    cd21216
    Location:143 → 257
    CH_ACTN_rpt2; second calponin homology (CH) domain found in the alpha-actinin family
Nucleotide Protein
Heading Accession and Version

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