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MLH3 mutL homolog 3 [ Saimiri boliviensis (Bolivian squirrel monkey) ]

Gene ID: 101028478, updated on 8-Mar-2024

Summary

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Gene symbol
MLH3
Gene description
mutL homolog 3
See related
EnsemblRapid:ENSSBOG00000018430
Gene type
protein coding
RefSeq status
MODEL
Organism
Saimiri boliviensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae; Saimiriinae; Saimiri
Orthologs
human mouse all
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Genomic context

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See MLH3 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
14
Annotation release Status Assembly Chr Location
102 current BCM_Sbol_2.0 (GCF_016699345.1) Unplaced Scaffold NW_024100921.1 (80194834..80231071, complement)

NW_024100921.1Genomic Context describing neighboring genes Neighboring gene placental growth factor Neighboring gene eukaryotic translation initiation factor 2B subunit beta Neighboring gene U6 spliceosomal RNA Neighboring gene acylphosphatase 1 Neighboring gene zinc finger C2HC-type containing 1C Neighboring gene NIMA related kinase 9 Neighboring gene phosphate carrier protein, mitochondrial-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_024100921 Unplaced Scaffold Reference BCM_Sbol_2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP-dependent DNA damage sensor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mismatched DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in mismatch repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of mismatch repair complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA mismatch repair protein Mlh3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Saimiri boliviensis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference BCM_Sbol_2.0 Primary Assembly

Genomic

  1. NW_024100921.1 Reference BCM_Sbol_2.0 Primary Assembly

    Range
    80194834..80231071 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039469341.1 → XP_039325275.1  DNA mismatch repair protein Mlh3 isoform X2

    UniProtKB/TrEMBL
    A0A2K6S9V7
    Conserved Domains (3) summary
    smart00853
    Location:1161 → 1340
    MutL_C; MutL C terminal dimerisation domain
    cd03486
    Location:206 → 349
    MutL_Trans_MLH3; transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to yeast and human MLH3 (MutL homologue 3). MLH3 belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain ...
    cd16926
    Location:9 → 192
    HATPase_MutL-MLH-PMS-like; Histidine kinase-like ATPase domain of DNA mismatch repair proteins Escherichia coli MutL, human MutL homologs (MLH/ PMS), and related domains

  2. XM_039469338.1 → XP_039325272.1  DNA mismatch repair protein Mlh3 isoform X1

    UniProtKB/TrEMBL
    A0A2K6S9V7
    Conserved Domains (3) summary
    smart00853
    Location:1194 → 1373
    MutL_C; MutL C terminal dimerisation domain
    cd03486
    Location:206 → 349
    MutL_Trans_MLH3; transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to yeast and human MLH3 (MutL homologue 3). MLH3 belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain ...
    cd16926
    Location:9 → 192
    HATPase_MutL-MLH-PMS-like; Histidine kinase-like ATPase domain of DNA mismatch repair proteins Escherichia coli MutL, human MutL homologs (MLH/ PMS), and related domains

  3. XM_039469340.1 → XP_039325274.1  DNA mismatch repair protein Mlh3 isoform X1

    UniProtKB/TrEMBL
    A0A2K6S9V7
    Conserved Domains (3) summary
    smart00853
    Location:1194 → 1373
    MutL_C; MutL C terminal dimerisation domain
    cd03486
    Location:206 → 349
    MutL_Trans_MLH3; transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to yeast and human MLH3 (MutL homologue 3). MLH3 belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain ...
    cd16926
    Location:9 → 192
    HATPase_MutL-MLH-PMS-like; Histidine kinase-like ATPase domain of DNA mismatch repair proteins Escherichia coli MutL, human MutL homologs (MLH/ PMS), and related domains

  4. XM_039469339.1 → XP_039325273.1  DNA mismatch repair protein Mlh3 isoform X1

    UniProtKB/TrEMBL
    A0A2K6S9V7
    Related
    ENSSBOP00000004180.2, ENSSBOT00000020429.2
    Conserved Domains (3) summary
    smart00853
    Location:1194 → 1373
    MutL_C; MutL C terminal dimerisation domain
    cd03486
    Location:206 → 349
    MutL_Trans_MLH3; transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to yeast and human MLH3 (MutL homologue 3). MLH3 belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain ...
    cd16926
    Location:9 → 192
    HATPase_MutL-MLH-PMS-like; Histidine kinase-like ATPase domain of DNA mismatch repair proteins Escherichia coli MutL, human MutL homologs (MLH/ PMS), and related domains

  5. XM_039469342.1 → XP_039325276.1  DNA mismatch repair protein Mlh3 isoform X3

    UniProtKB/TrEMBL
    A0A2K6S9V7
    Conserved Domains (4) summary
    smart00853
    Location:1194 → 1279
    MutL_C; MutL C terminal dimerisation domain
    COG0323
    Location:1054 → 1278
    MutL; DNA mismatch repair ATPase MutL [Replication, recombination and repair]
    cd03486
    Location:206 → 349
    MutL_Trans_MLH3; transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to yeast and human MLH3 (MutL homologue 3). MLH3 belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain ...
    cd16926
    Location:9 → 192
    HATPase_MutL-MLH-PMS-like; Histidine kinase-like ATPase domain of DNA mismatch repair proteins Escherichia coli MutL, human MutL homologs (MLH/ PMS), and related domains

  6. XM_039469343.1 → XP_039325277.1  DNA mismatch repair protein Mlh3 isoform X4

    UniProtKB/TrEMBL
    A0A2K6S9V7
    Related
    ENSSBOP00000004184.2, ENSSBOT00000020433.2
    Conserved Domains (4) summary
    smart00853
    Location:1194 → 1280
    MutL_C; MutL C terminal dimerisation domain
    COG0323
    Location:1054 → 1280
    MutL; DNA mismatch repair ATPase MutL [Replication, recombination and repair]
    cd03486
    Location:206 → 349
    MutL_Trans_MLH3; transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to yeast and human MLH3 (MutL homologue 3). MLH3 belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain ...
    cd16926
    Location:9 → 192
    HATPase_MutL-MLH-PMS-like; Histidine kinase-like ATPase domain of DNA mismatch repair proteins Escherichia coli MutL, human MutL homologs (MLH/ PMS), and related domains

RNA

  1. XR_005579384.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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