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FANCM FA complementation group M [ Pan paniscus (pygmy chimpanzee) ]

Gene ID: 100988683, updated on 8-Mar-2024

Summary

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Gene symbol
FANCM
Gene description
FA complementation group M
See related
Ensembl:ENSPPAG00000028944
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan paniscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 15
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanPan1-v2.0_pri (GCF_029289425.2) 15 NC_073264.2 (46307022..46373092)
RS_2023_05 previous assembly NHGRI_mPanPan1-v1.1-0.1.freeze_pri (GCF_029289425.1) 14 NC_073263.1 (45523532..45589603)

Chromosome 15 - NC_073264.2Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORD58 Neighboring gene pre-mRNA processing factor 39 Neighboring gene small nucleolar RNA SNORD127 Neighboring gene FKBP prolyl isomerase 3 Neighboring gene MIS18 binding protein 1 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3'-5' DNA helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables four-way junction DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables four-way junction helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in double-strand break repair via synthesis-dependent strand annealing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in interstrand cross-link repair IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
Fanconi anemia group M protein
Names
Fanconi anemia complementation group M

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029289425.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

Genomic

  1. NC_073264.2 Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

    Range
    46307022..46373092
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_055097552.1 → XP_054953527.1  Fanconi anemia group M protein isoform X1

    UniProtKB/TrEMBL
    A0A2R9A3N5

  2. XM_003831753.5 → XP_003831801.1  Fanconi anemia group M protein isoform X1

    UniProtKB/TrEMBL
    A0A2R9A3N5
    Related
    ENSPPAP00000011489.1
    Conserved Domains (7) summary
    COG1111
    Location:83 → 617
    MPH1; ERCC4-related helicase [Replication, recombination and repair]
    cd00046
    Location:106 → 248
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd12091
    Location:298 → 413
    FANCM_ID; Insert domain of FANCM and related proteins
    pfam00271
    Location:472 → 579
    Helicase_C; Helicase conserved C-terminal domain
    pfam02732
    Location:1841 → 1948
    ERCC4; ERCC4 domain
    pfam09444
    Location:1508 → 1588
    MRC1; MRC1-like domain
    pfam16783
    Location:675 → 789
    FANCM-MHF_bd; FANCM to MHF binding domain

  3. XM_063596066.1 → XP_063452136.1  Fanconi anemia group M protein isoform X3

  4. XM_057299675.2 → XP_057155658.1  Fanconi anemia group M protein isoform X2

Nucleotide Protein
Heading Accession and Version

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