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DERL2 derlin 2 [ Pan paniscus (pygmy chimpanzee) ]

Gene ID: 100975730, updated on 8-Mar-2024

Summary

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Gene symbol
DERL2
Gene description
derlin 2
See related
Ensembl:ENSPPAG00000029561
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan paniscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See DERL2 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanPan1-v2.0_pri (GCF_029289425.2) 19 NC_073268.2 (13084405..13096337, complement)
RS_2023_05 previous assembly NHGRI_mPanPan1-v1.1-0.1.freeze_pri (GCF_029289425.1) 17 NC_073266.1 (15049592..15064585, complement)

Chromosome 19 - NC_073268.2Genomic Context describing neighboring genes Neighboring gene complement C1q binding protein Neighboring gene DEAH-box helicase 33 Neighboring gene uncharacterized LOC130540917 Neighboring gene uncharacterized LOC100973474 Neighboring gene MIS12 kinetochore complex component Neighboring gene NLR family pyrin domain containing 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables misfolded protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin-specific protease binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in endoplasmic reticulum unfolded protein response IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of Hrd1p ubiquitin ligase ERAD-L complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
derlin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029289425.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

Genomic

  1. NC_073268.2 Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

    Range
    13084405..13096337 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014341934.5 → XP_014197420.3  derlin-2 isoform X2

  2. XM_003810162.6 → XP_003810210.1  derlin-2 isoform X1

    See identical proteins and their annotated locations for XP_003810210.1

    Related
    ENSPPAP00000012773.1
    Conserved Domains (1) summary
    pfam04511
    Location:25 → 214
    DER1; Der1-like family

  3. XM_034941378.3 → XP_034797269.1  derlin-2 isoform X3

    Conserved Domains (1) summary
    pfam04511
    Location:13 → 181
    DER1; Der1-like family

  4. XM_055101015.1 → XP_054956990.1  derlin-2 isoform X4

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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