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SMARCA2 SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2 [ Pan paniscus (pygmy chimpanzee) ]

Gene ID: 100975588, updated on 20-Sep-2024

Summary

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Gene symbol
SMARCA2
Gene description
SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2
See related
Ensembl:ENSPPAG00000038717
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan paniscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 11
Exon count:
40
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanPan1-v2.0_pri (GCF_029289425.2) 11 NC_073260.2 (122394494..122574119, complement)
RS_2023_05 previous assembly NHGRI_mPanPan1-v1.1-0.1.freeze_pri (GCF_029289425.1) 9 NC_073258.1 (122400390..122580062, complement)

Chromosome 11 - NC_073260.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC129393110 Neighboring gene very low density lipoprotein receptor Neighboring gene uncharacterized LOC106635092 Neighboring gene U2 spliceosomal RNA Neighboring gene uncharacterized LOC117981619 Neighboring gene uncharacterized LOC134728551

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP-dependent chromatin remodeler activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chromatin remodeling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in transcription elongation by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of RSC-type complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
probable global transcription activator SNF2L2
Names
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029289425.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

Genomic

  1. NC_073260.2 Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

    Range
    122394494..122574119 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063594038.1 → XP_063450108.1  probable global transcription activator SNF2L2 isoform X4

    UniProtKB/TrEMBL
    A0A2R9BSE0

  2. XM_057298775.2 → XP_057154758.1  probable global transcription activator SNF2L2 isoform X2

    UniProtKB/TrEMBL
    A0A2R9BSE0

  3. XM_063594037.1 → XP_063450107.1  probable global transcription activator SNF2L2 isoform X3

    UniProtKB/TrEMBL
    A0A2R9BSE0

  4. XM_034967063.3 → XP_034822954.1  probable global transcription activator SNF2L2 isoform X1

    UniProtKB/TrEMBL
    A0A2R9BSE0
    Conserved Domains (10) summary
    cd05516
    Location:1376 → 1500
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00573
    Location:430 → 502
    HSA; domain in helicases and associated with SANT domains
    PLN03142
    Location:714 → 1196
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG4942
    Location:314 → 521
    EnvC; Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning]
    pfam15822
    Location:45 → 162
    MISS; MAPK-interacting and spindle-stabilizing protein-like
    cd18063
    Location:695 → 945
    DEXHc_SMARCA2; DEXH-box helicase domain of SMARCA2
    pfam07533
    Location:584 → 626
    BRK; BRK domain
    pfam08880
    Location:173 → 207
    QLQ
    pfam14619
    Location:1254 → 1320
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
    cl02556
    Location:1327 → 1413
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

  5. XM_034967067.3 → XP_034822958.1  probable global transcription activator SNF2L2 isoform X1

    UniProtKB/TrEMBL
    A0A2R9BSE0
    Conserved Domains (10) summary
    cd05516
    Location:1376 → 1500
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00573
    Location:430 → 502
    HSA; domain in helicases and associated with SANT domains
    PLN03142
    Location:714 → 1196
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG4942
    Location:314 → 521
    EnvC; Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning]
    pfam15822
    Location:45 → 162
    MISS; MAPK-interacting and spindle-stabilizing protein-like
    cd18063
    Location:695 → 945
    DEXHc_SMARCA2; DEXH-box helicase domain of SMARCA2
    pfam07533
    Location:584 → 626
    BRK; BRK domain
    pfam08880
    Location:173 → 207
    QLQ
    pfam14619
    Location:1254 → 1320
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
    cl02556
    Location:1327 → 1413
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

  6. XM_055092199.2 → XP_054948174.1  probable global transcription activator SNF2L2 isoform X1

    UniProtKB/TrEMBL
    A0A2R9BSE0

  7. XM_034967065.3 → XP_034822956.1  probable global transcription activator SNF2L2 isoform X1

    UniProtKB/TrEMBL
    A0A2R9BSE0
    Conserved Domains (10) summary
    cd05516
    Location:1376 → 1500
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00573
    Location:430 → 502
    HSA; domain in helicases and associated with SANT domains
    PLN03142
    Location:714 → 1196
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG4942
    Location:314 → 521
    EnvC; Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning]
    pfam15822
    Location:45 → 162
    MISS; MAPK-interacting and spindle-stabilizing protein-like
    cd18063
    Location:695 → 945
    DEXHc_SMARCA2; DEXH-box helicase domain of SMARCA2
    pfam07533
    Location:584 → 626
    BRK; BRK domain
    pfam08880
    Location:173 → 207
    QLQ
    pfam14619
    Location:1254 → 1320
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
    cl02556
    Location:1327 → 1413
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

  8. XM_034967064.3 → XP_034822955.1  probable global transcription activator SNF2L2 isoform X1

    UniProtKB/TrEMBL
    A0A2R9BSE0
    Conserved Domains (10) summary
    cd05516
    Location:1376 → 1500
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00573
    Location:430 → 502
    HSA; domain in helicases and associated with SANT domains
    PLN03142
    Location:714 → 1196
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG4942
    Location:314 → 521
    EnvC; Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning]
    pfam15822
    Location:45 → 162
    MISS; MAPK-interacting and spindle-stabilizing protein-like
    cd18063
    Location:695 → 945
    DEXHc_SMARCA2; DEXH-box helicase domain of SMARCA2
    pfam07533
    Location:584 → 626
    BRK; BRK domain
    pfam08880
    Location:173 → 207
    QLQ
    pfam14619
    Location:1254 → 1320
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
    cl02556
    Location:1327 → 1413
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

  9. XM_034967066.3 → XP_034822957.1  probable global transcription activator SNF2L2 isoform X1

    UniProtKB/TrEMBL
    A0A2R9BSE0
    Conserved Domains (10) summary
    cd05516
    Location:1376 → 1500
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00573
    Location:430 → 502
    HSA; domain in helicases and associated with SANT domains
    PLN03142
    Location:714 → 1196
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG4942
    Location:314 → 521
    EnvC; Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning]
    pfam15822
    Location:45 → 162
    MISS; MAPK-interacting and spindle-stabilizing protein-like
    cd18063
    Location:695 → 945
    DEXHc_SMARCA2; DEXH-box helicase domain of SMARCA2
    pfam07533
    Location:584 → 626
    BRK; BRK domain
    pfam08880
    Location:173 → 207
    QLQ
    pfam14619
    Location:1254 → 1320
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
    cl02556
    Location:1327 → 1413
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

  10. XM_034967070.4 → XP_034822961.1  probable global transcription activator SNF2L2 isoform X6

    Conserved Domains (2) summary
    cd05516
    Location:58 → 164
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    cl02556
    Location:9 → 71
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

  11. XM_063594039.1 → XP_063450109.1  probable global transcription activator SNF2L2 isoform X5

    UniProtKB/TrEMBL
    A0A2R9BSK6

  12. XM_057298776.2 → XP_057154759.1  probable global transcription activator SNF2L2 isoform X5

    UniProtKB/TrEMBL
    A0A2R9BSK6

  13. XM_055092203.2 → XP_054948178.1  probable global transcription activator SNF2L2 isoform X5

    UniProtKB/TrEMBL
    A0A2R9BSK6

  14. XM_055092201.2 → XP_054948176.1  probable global transcription activator SNF2L2 isoform X5

    UniProtKB/TrEMBL
    A0A2R9BSK6
Nucleotide Protein
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