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ERCC5 ERCC excision repair 5, endonuclease [ Canis lupus familiaris (dog) ]

Gene ID: 100855935, updated on 8-Mar-2024

Summary

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Gene symbol
ERCC5
Gene description
ERCC excision repair 5, endonuclease
See related
Ensembl:ENSCAFG00845027609
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See ERCC5 in Genome Data Viewer
Location:
chromosome: 22
Exon count:
18
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 22 NC_051826.1 (52786543..52820389)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 22 NC_006604.4 (52118439..52152268)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 22 NC_049243.1 (52496357..52530203)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 22 NC_049282.1 (52438966..52472791)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 22 NC_049763.1 (52455293..52489134)

Chromosome 22 - NC_051826.1Genomic Context describing neighboring genes Neighboring gene protein O-glucosyltransferase 2 Neighboring gene uncharacterized LOC111091702 Neighboring gene basic, immunoglobulin-like variable motif containing Neighboring gene uncharacterized LOC119865227 Neighboring gene putative methyltransferase-like protein 21E Neighboring gene uncharacterized LOC119865229

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA endonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in nucleotide-excision repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA repair protein complementing XP-G cells
Names
excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G (Cockayne syndrome))

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051826.1 Reference ROS_Cfam_1.0

    Range
    52786543..52820389
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038431423.1 → XP_038287351.1  DNA repair protein complementing XP-G cells isoform X5

    UniProtKB/TrEMBL
    A0A8C0TT61
    Conserved Domains (1) summary
    TIGR00600
    Location:100 → 953
    rad2; DNA excision repair protein (rad2)

  2. XM_038431419.1 → XP_038287347.1  DNA repair protein complementing XP-G cells isoform X1

    UniProtKB/TrEMBL
    A0A8C0MHW3, A0A8C0TT61, A0A8I3PZL5
    Related
    ENSCAFP00845038206.1, ENSCAFT00845048699.1
    Conserved Domains (1) summary
    TIGR00600
    Location:1 → 1030
    rad2; DNA excision repair protein (rad2)

  3. XM_038431420.1 → XP_038287348.1  DNA repair protein complementing XP-G cells isoform X2

    UniProtKB/TrEMBL
    A0A8C0MHW3, A0A8C0TT61, A0A8I3PZL5
    Conserved Domains (1) summary
    TIGR00600
    Location:1 → 1030
    rad2; DNA excision repair protein (rad2)

  4. XM_038431421.1 → XP_038287349.1  DNA repair protein complementing XP-G cells isoform X3

    UniProtKB/TrEMBL
    A0A8C0TT61
    Conserved Domains (1) summary
    TIGR00600
    Location:1 → 970
    rad2; DNA excision repair protein (rad2)

  5. XM_038431424.1 → XP_038287352.1  DNA repair protein complementing XP-G cells isoform X6

    UniProtKB/TrEMBL
    A0A8C0R595
    Conserved Domains (1) summary
    TIGR00600
    Location:1 → 960
    rad2; DNA excision repair protein (rad2)

  6. XM_038431425.1 → XP_038287353.1  DNA repair protein complementing XP-G cells isoform X7

    Conserved Domains (1) summary
    TIGR00600
    Location:1 → 894
    rad2; DNA excision repair protein (rad2)

  7. XM_038431428.1 → XP_038287356.1  DNA repair protein complementing XP-G cells isoform X9

    Conserved Domains (1) summary
    TIGR00600
    Location:1 → 894
    rad2; DNA excision repair protein (rad2)

  8. XM_038431426.1 → XP_038287354.1  DNA repair protein complementing XP-G cells isoform X8

    Conserved Domains (1) summary
    TIGR00600
    Location:1 → 896
    rad2; DNA excision repair protein (rad2)

  9. XM_038431427.1 → XP_038287355.1  DNA repair protein complementing XP-G cells isoform X8

    Conserved Domains (1) summary
    TIGR00600
    Location:1 → 896
    rad2; DNA excision repair protein (rad2)

  10. XM_038431429.1 → XP_038287357.1  DNA repair protein complementing XP-G cells isoform X10

    Conserved Domains (1) summary
    TIGR00600
    Location:1 → 894
    rad2; DNA excision repair protein (rad2)

  11. XM_038431422.1 → XP_038287350.1  DNA repair protein complementing XP-G cells isoform X4

    UniProtKB/TrEMBL
    A0A8C0TT61
    Conserved Domains (1) summary
    TIGR00600
    Location:1 → 958
    rad2; DNA excision repair protein (rad2)

RNA

  1. XR_005299603.1 RNA Sequence

  2. XR_005299604.1 RNA Sequence

  3. XR_005299605.1 RNA Sequence

  4. XR_005299606.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049282.1 Alternate UMICH_Zoey_3.1

    Range
    52438966..52472791
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038506803.1 → XP_038362731.1  DNA repair protein complementing XP-G cells isoform X5

  2. XM_038506798.1 → XP_038362726.1  DNA repair protein complementing XP-G cells isoform X1

  3. XM_038506799.1 → XP_038362727.1  DNA repair protein complementing XP-G cells isoform X2

  4. XM_038506804.1 → XP_038362732.1  DNA repair protein complementing XP-G cells isoform X6

    Conserved Domains (1) summary
    TIGR00600
    Location:1 → 960
    rad2; DNA excision repair protein (rad2)

  5. XM_038506805.1 → XP_038362733.1  DNA repair protein complementing XP-G cells isoform X7

    Conserved Domains (1) summary
    TIGR00600
    Location:1 → 894
    rad2; DNA excision repair protein (rad2)

  6. XM_038506809.1 → XP_038362737.1  DNA repair protein complementing XP-G cells isoform X9

    Conserved Domains (1) summary
    TIGR00600
    Location:1 → 894
    rad2; DNA excision repair protein (rad2)

  7. XM_038506806.1 → XP_038362734.1  DNA repair protein complementing XP-G cells isoform X8

    Conserved Domains (1) summary
    TIGR00600
    Location:1 → 896
    rad2; DNA excision repair protein (rad2)

  8. XM_038506807.1 → XP_038362735.1  DNA repair protein complementing XP-G cells isoform X8

    Conserved Domains (1) summary
    TIGR00600
    Location:1 → 896
    rad2; DNA excision repair protein (rad2)

  9. XM_038506810.1 → XP_038362738.1  DNA repair protein complementing XP-G cells isoform X10

    Conserved Domains (1) summary
    TIGR00600
    Location:1 → 894
    rad2; DNA excision repair protein (rad2)

  10. XM_038506800.1 → XP_038362728.1  DNA repair protein complementing XP-G cells isoform X3

  11. XM_038506801.1 → XP_038362729.1  DNA repair protein complementing XP-G cells isoform X4

RNA

  1. XR_005342723.1 RNA Sequence

  2. XR_005342724.1 RNA Sequence

  3. XR_005342725.1 RNA Sequence

  4. XR_005342726.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049763.1 Alternate UNSW_CanFamBas_1.0

    Range
    52455293..52489134
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038634166.1 → XP_038490094.1  DNA repair protein complementing XP-G cells isoform X5

  2. XM_038634162.1 → XP_038490090.1  DNA repair protein complementing XP-G cells isoform X1

  3. XM_038634163.1 → XP_038490091.1  DNA repair protein complementing XP-G cells isoform X2

  4. XM_038634164.1 → XP_038490092.1  DNA repair protein complementing XP-G cells isoform X3

  5. XM_038634167.1 → XP_038490095.1  DNA repair protein complementing XP-G cells isoform X6

  6. XM_038634168.1 → XP_038490096.1  DNA repair protein complementing XP-G cells isoform X7

  7. XM_038634171.1 → XP_038490099.1  DNA repair protein complementing XP-G cells isoform X9

  8. XM_038634169.1 → XP_038490097.1  DNA repair protein complementing XP-G cells isoform X8

  9. XM_038634170.1 → XP_038490098.1  DNA repair protein complementing XP-G cells isoform X8

  10. XM_038634172.1 → XP_038490100.1  DNA repair protein complementing XP-G cells isoform X10

  11. XM_038634165.1 → XP_038490093.1  DNA repair protein complementing XP-G cells isoform X4

RNA

  1. XR_005410453.1 RNA Sequence

  2. XR_005410454.1 RNA Sequence

  3. XR_005410455.1 RNA Sequence

  4. XR_005410456.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049243.1 Alternate UU_Cfam_GSD_1.0

    Range
    52496357..52530203
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038570006.1 → XP_038425934.1  DNA repair protein complementing XP-G cells isoform X5

    UniProtKB/TrEMBL
    A0A8C0TT61

  2. XM_038570001.1 → XP_038425929.1  DNA repair protein complementing XP-G cells isoform X1

    UniProtKB/TrEMBL
    A0A8C0TT61

  3. XM_038570003.1 → XP_038425931.1  DNA repair protein complementing XP-G cells isoform X2

    UniProtKB/TrEMBL
    A0A8C0TT61

  4. XM_038570007.1 → XP_038425935.1  DNA repair protein complementing XP-G cells isoform X6

    UniProtKB/TrEMBL
    A0A8C0R595

  5. XM_038570008.1 → XP_038425936.1  DNA repair protein complementing XP-G cells isoform X7

  6. XM_038570012.1 → XP_038425940.1  DNA repair protein complementing XP-G cells isoform X9

  7. XM_038570009.1 → XP_038425937.1  DNA repair protein complementing XP-G cells isoform X8

  8. XM_038570010.1 → XP_038425938.1  DNA repair protein complementing XP-G cells isoform X8

  9. XM_038570013.1 → XP_038425941.1  DNA repair protein complementing XP-G cells isoform X10

  10. XM_038570004.1 → XP_038425932.1  DNA repair protein complementing XP-G cells isoform X3

    UniProtKB/TrEMBL
    A0A8C0TT61

  11. XM_038570005.1 → XP_038425933.1  DNA repair protein complementing XP-G cells isoform X4

    UniProtKB/TrEMBL
    A0A8C0TT61

RNA

  1. XR_005376546.1 RNA Sequence

  2. XR_005376547.1 RNA Sequence

  3. XR_005376548.1 RNA Sequence

  4. XR_005376549.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006604.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    52118439..52152268
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022408138.2 → XP_022263846.1  DNA repair protein complementing XP-G cells isoform X5

    UniProtKB/TrEMBL
    A0A8C0TT61
    Conserved Domains (1) summary
    cl26305
    Location:100 → 953
    XPG_I; XPG I-region

  2. XM_003639812.5 → XP_003639860.1  DNA repair protein complementing XP-G cells isoform X1

    UniProtKB/TrEMBL
    A0A8C0TT61, A0A8P0SVU5
    Conserved Domains (1) summary
    TIGR00600
    Location:1 → 1030
    rad2; DNA excision repair protein (rad2)

  3. XM_038456746.1 → XP_038312674.1  DNA repair protein complementing XP-G cells isoform X2

    UniProtKB/TrEMBL
    A0A8C0TT61, A0A8P0SVU5
    Conserved Domains (1) summary
    TIGR00600
    Location:1 → 1030
    rad2; DNA excision repair protein (rad2)

  4. XM_022408137.2 → XP_022263845.1  DNA repair protein complementing XP-G cells isoform X3

    UniProtKB/TrEMBL
    A0A8C0TT61
    Conserved Domains (1) summary
    cl26305
    Location:1 → 970
    XPG_I; XPG I-region

  5. XM_005634067.4 → XP_005634124.1  DNA repair protein complementing XP-G cells isoform X6

    UniProtKB/TrEMBL
    A0A8C0R595
    Conserved Domains (3) summary
    cd09904
    Location:850 → 944
    H3TH_XPG; H3TH domain of Xeroderma pigmentosum complementation group G (XPG) nuclease, a structure-specific, divalent-metal-ion dependent, 5' nuclease
    cd09868
    Location:1 → 130
    PIN_XPG; PIN domain of Xeroderma pigmentosum complementation group G (XPG) nuclease, a structure-specific, divalent-metal-ion dependent, 5' nuclease and homologs
    TIGR00600
    Location:1 → 960
    rad2; DNA excision repair protein (rad2)

  6. XM_022408140.2 → XP_022263848.1  DNA repair protein complementing XP-G cells isoform X7

    Conserved Domains (1) summary
    cl26305
    Location:1 → 894
    XPG_I; XPG I-region

  7. XM_022408144.2 → XP_022263852.1  DNA repair protein complementing XP-G cells isoform X9

    Conserved Domains (1) summary
    cl26305
    Location:1 → 894
    XPG_I; XPG I-region

  8. XM_022408142.2 → XP_022263850.1  DNA repair protein complementing XP-G cells isoform X8

    Conserved Domains (1) summary
    TIGR00600
    Location:1 → 896
    rad2; DNA excision repair protein (rad2)

  9. XM_038456747.1 → XP_038312675.1  DNA repair protein complementing XP-G cells isoform X8

    Conserved Domains (1) summary
    TIGR00600
    Location:1 → 896
    rad2; DNA excision repair protein (rad2)

  10. XM_022408145.2 → XP_022263853.1  DNA repair protein complementing XP-G cells isoform X10

    Conserved Domains (1) summary
    cl26305
    Location:1 → 894
    XPG_I; XPG I-region

  11. XM_014106332.3 → XP_013961807.1  DNA repair protein complementing XP-G cells isoform X4

    UniProtKB/TrEMBL
    A0A8C0TT61
    Conserved Domains (4) summary
    cd09904
    Location:778 → 872
    H3TH_XPG; H3TH domain of Xeroderma pigmentosum complementation group G (XPG) nuclease, a structure-specific, divalent-metal-ion dependent, 5' nuclease
    cd09868
    Location:663 → 911
    PIN_XPG; PIN domain of Xeroderma pigmentosum complementation group G (XPG) nuclease, a structure-specific, divalent-metal-ion dependent, 5' nuclease and homologs
    TIGR00600
    Location:1 → 958
    rad2; DNA excision repair protein (rad2)
    cl14812
    Location:1 → 58
    PIN_SF; PIN (PilT N terminus) domain: Superfamily

RNA

  1. XR_005313408.1 RNA Sequence

  2. XR_005313409.1 RNA Sequence

  3. XR_002617648.2 RNA Sequence

  4. XR_002617649.2 RNA Sequence

Nucleotide Protein
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