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SCN9A sodium voltage-gated channel alpha subunit 9 [ Canis lupus familiaris (dog) ]

Gene ID: 100855710, updated on 8-Mar-2024

Summary

Official Symbol
SCN9Aprovided by VGNC
Official Full Name
sodium voltage-gated channel alpha subunit 9provided by VGNC
Primary source
VGNC:VGNC:45924
See related
Ensembl:ENSCAFG00845017751
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Try the new Transcript table

Genomic context

See SCN9A in Genome Data Viewer
Location:
chromosome: 36
Exon count:
27
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 36 NC_051840.1 (11421333..11580725, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 36 NC_006618.4 (11431905..11590849, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 36 NC_049257.1 (11588422..11748250, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 36 NC_049296.1 (11503582..11662869, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 36 NC_049777.1 (11475664..11634434, complement)

Chromosome 36 - NC_051840.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111094186 Neighboring gene tetratricopeptide repeat domain 21B Neighboring gene protein CEBPZOS-like Neighboring gene sodium voltage-gated channel alpha subunit 1 Neighboring gene uncharacterized LOC119867819 Neighboring gene uncharacterized LOC119867818 Neighboring gene uncharacterized LOC102153897 Neighboring gene uncharacterized LOC119867820 Neighboring gene sodium voltage-gated channel alpha subunit 7

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables voltage-gated sodium channel activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in membrane depolarization during action potential IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in neuronal action potential IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in sodium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
part_of voltage-gated sodium channel complex IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
sodium channel protein type 9 subunit alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051840.1 Reference ROS_Cfam_1.0

    Range
    11421333..11580725 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038446944.1XP_038302872.1  sodium channel protein type 9 subunit alpha isoform X2

    UniProtKB/TrEMBL
    A0A8C0TWN1, A0A8I3P4Z8
    Related
    ENSCAFP00845024965.1, ENSCAFT00845031924.1
    Conserved Domains (5) summary
    cd13433
    Location:14461498
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:11791454
    Ion_trans; Ion transport protein
    pfam06512
    Location:9701175
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:488682
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:17701817
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
  2. XM_038446943.1XP_038302871.1  sodium channel protein type 9 subunit alpha isoform X1

    UniProtKB/TrEMBL
    A0A8C0TWN1, A0A8I3P4Z8
    Related
    ENSCAFP00845024858.1, ENSCAFT00845031763.1
    Conserved Domains (5) summary
    cd13433
    Location:14571509
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:11901465
    Ion_trans; Ion transport protein
    pfam06512
    Location:9811186
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:488693
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:17811828
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
  3. XM_038446946.1XP_038302874.1  sodium channel protein type 9 subunit alpha isoform X4

    UniProtKB/TrEMBL
    A0A8C0TTJ9
    Related
    ENSCAFP00845024657.1, ENSCAFT00845031487.1
    Conserved Domains (5) summary
    cd13433
    Location:13461398
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:10791354
    Ion_trans; Ion transport protein
    pfam06512
    Location:8701075
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:377582
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:16701717
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
  4. XM_038446945.1XP_038302873.1  sodium channel protein type 9 subunit alpha isoform X3

    UniProtKB/TrEMBL
    A0A8C0TU97, A0A8I3P301
    Conserved Domains (5) summary
    cd13433
    Location:12091261
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:9421217
    Ion_trans; Ion transport protein
    pfam06512
    Location:733938
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:240445
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:15331580
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049296.1 Alternate UMICH_Zoey_3.1

    Range
    11503582..11662869 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038521016.1XP_038376944.1  sodium channel protein type 9 subunit alpha isoform X2

    Conserved Domains (5) summary
    cd13433
    Location:14461498
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:11791454
    Ion_trans; Ion transport protein
    pfam06512
    Location:9701175
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:488682
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:17701817
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
  2. XM_038521015.1XP_038376943.1  sodium channel protein type 9 subunit alpha isoform X1

    Conserved Domains (5) summary
    cd13433
    Location:14571509
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:11901465
    Ion_trans; Ion transport protein
    pfam06512
    Location:9811186
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:488693
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:17811828
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
  3. XM_038521018.1XP_038376946.1  sodium channel protein type 9 subunit alpha isoform X4

    Conserved Domains (5) summary
    cd13433
    Location:13461398
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:10791354
    Ion_trans; Ion transport protein
    pfam06512
    Location:8701075
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:377582
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:16701717
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
  4. XM_038521017.1XP_038376945.1  sodium channel protein type 9 subunit alpha isoform X3

    Conserved Domains (5) summary
    cd13433
    Location:12091261
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:9421217
    Ion_trans; Ion transport protein
    pfam06512
    Location:733938
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:240445
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:15331580
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049777.1 Alternate UNSW_CanFamBas_1.0

    Range
    11475664..11634434 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038649133.1XP_038505061.1  sodium channel protein type 9 subunit alpha isoform X2

  2. XM_038649132.1XP_038505060.1  sodium channel protein type 9 subunit alpha isoform X1

  3. XM_038649135.1XP_038505063.1  sodium channel protein type 9 subunit alpha isoform X4

  4. XM_038649134.1XP_038505062.1  sodium channel protein type 9 subunit alpha isoform X3

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049257.1 Alternate UU_Cfam_GSD_1.0

    Range
    11588422..11748250 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038584714.1XP_038440642.1  sodium channel protein type 9 subunit alpha isoform X2

    UniProtKB/TrEMBL
    A0A8C0TWN1, A0A8I3P4Z8
    Conserved Domains (5) summary
    cd13433
    Location:14461498
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:11791454
    Ion_trans; Ion transport protein
    pfam06512
    Location:9701175
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:488682
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:17701817
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
  2. XM_038584713.1XP_038440641.1  sodium channel protein type 9 subunit alpha isoform X1

    UniProtKB/TrEMBL
    A0A8C0TWN1, A0A8I3P4Z8
    Conserved Domains (5) summary
    cd13433
    Location:14571509
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:11901465
    Ion_trans; Ion transport protein
    pfam06512
    Location:9811186
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:488693
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:17811828
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
  3. XM_038584716.1XP_038440644.1  sodium channel protein type 9 subunit alpha isoform X4

    UniProtKB/TrEMBL
    A0A8C0TTJ9
    Conserved Domains (5) summary
    cd13433
    Location:13461398
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:10791354
    Ion_trans; Ion transport protein
    pfam06512
    Location:8701075
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:377582
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:16701717
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
  4. XM_038584715.1XP_038440643.1  sodium channel protein type 9 subunit alpha isoform X3

    UniProtKB/TrEMBL
    A0A8C0TU97, A0A8I3P301
    Conserved Domains (5) summary
    cd13433
    Location:12091261
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:9421217
    Ion_trans; Ion transport protein
    pfam06512
    Location:733938
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:240445
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:15331580
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006618.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    11431905..11590849 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038463448.1XP_038319376.1  sodium channel protein type 9 subunit alpha isoform X2

    UniProtKB/TrEMBL
    A0A8C0TWN1, A0A8I3P4Z8
    Conserved Domains (5) summary
    cd13433
    Location:14461498
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:11791454
    Ion_trans; Ion transport protein
    pfam06512
    Location:9701175
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:488682
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:17701817
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
  2. XM_038463447.1XP_038319375.1  sodium channel protein type 9 subunit alpha isoform X1

    UniProtKB/TrEMBL
    A0A8C0TWN1, A0A8I3P4Z8
    Conserved Domains (5) summary
    cd13433
    Location:14571509
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:11901465
    Ion_trans; Ion transport protein
    pfam06512
    Location:9811186
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:488693
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:17811828
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
  3. XM_022414844.1XP_022270552.1  sodium channel protein type 9 subunit alpha isoform X4

    UniProtKB/TrEMBL
    A0A8C0TTJ9
    Conserved Domains (5) summary
    cd13433
    Location:13461398
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:10791354
    Ion_trans; Ion transport protein
    pfam06512
    Location:8701075
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:377582
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:16701717
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
  4. XM_022414843.1XP_022270551.1  sodium channel protein type 9 subunit alpha isoform X3

    UniProtKB/TrEMBL
    A0A8C0TU97, A0A8I3P301
    Conserved Domains (5) summary
    cd13433
    Location:12091261
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:9421217
    Ion_trans; Ion transport protein
    pfam06512
    Location:733938
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:240445
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:15331580
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated