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Arhgap12 Rho GTPase activating protein 12 [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100770897, updated on 8-Mar-2024

Summary

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Gene symbol
Arhgap12
Gene description
Rho GTPase activating protein 12
See related
Ensembl:ENSCGRG00015026683
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
human mouse all
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Genomic context

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See Arhgap12 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
18
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003613708.1 (2468569..2550083)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 3 NC_048596.1 (208326939..208425162)

NW_003613708.1Genomic Context describing neighboring genes Neighboring gene kinesin family member 5B Neighboring gene 40S ribosomal protein S28-like Neighboring gene uncharacterized LOC118238464 Neighboring gene uncharacterized LOC113834634

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho GTPase-activating protein 12

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003613708.1 Reference CriGri_1.0 Primary Assembly

    Range
    2468569..2550083
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027423904.2 → XP_027279705.1  rho GTPase-activating protein 12 isoform X1

    UniProtKB/TrEMBL
    A0A8C2N892, A0A8C2N8A2

  2. XM_027423908.2 → XP_027279709.1  rho GTPase-activating protein 12 isoform X2

    UniProtKB/TrEMBL
    A0A8C2MZW1, A0A8C2N8A2

  3. XM_027423915.2 → XP_027279716.1  rho GTPase-activating protein 12 isoform X3

    UniProtKB/TrEMBL
    A0A8C2N0F7, G3H3P6

  4. XM_027423922.2 → XP_027279723.1  rho GTPase-activating protein 12 isoform X4

    UniProtKB/TrEMBL
    A0A8C2N0F7, A0A9J7FNA7

  5. XM_016973027.2 → XP_016828516.1  rho GTPase-activating protein 12 isoform X5

    UniProtKB/TrEMBL
    A0A8C2N0F7, A0A9J7JJI6
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    cd00201
    Location:266 → 296
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd04403
    Location:574 → 759
    RhoGAP_ARHGAP27_15_12_9; RhoGAP_ARHGAP27_15_12_9: GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. ...
    cd13233
    Location:385 → 496
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam00169
    Location:395 → 494
    PH; PH domain
    pfam16618
    Location:69 → 264
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048596.1 Alternate CriGri-PICRH-1.0

    Range
    208326939..208425162
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027405470.2 → XP_027261271.1  rho GTPase-activating protein 12 isoform X1

    UniProtKB/TrEMBL
    A0A8C2N892, A0A8C2N8A2
    Related
    ENSCGRP00015035615.1, ENSCGRT00015043429.2

  2. XM_027405471.2 → XP_027261272.1  rho GTPase-activating protein 12 isoform X2

    UniProtKB/TrEMBL
    A0A8C2MZW1, A0A8C2N8A2
    Related
    ENSCGRP00015035644.1, ENSCGRT00015043468.2

  3. XM_027405472.2 → XP_027261273.1  rho GTPase-activating protein 12 isoform X3

    UniProtKB/TrEMBL
    A0A8C2N0F7, G3H3P6
    Related
    ENSCGRP00015035657.1, ENSCGRT00015043484.2

  4. XM_027405473.2 → XP_027261274.1  rho GTPase-activating protein 12 isoform X4

    UniProtKB/TrEMBL
    A0A8C2N0F7, A0A9J7FNA7

  5. XM_027405474.2 → XP_027261275.1  rho GTPase-activating protein 12 isoform X5

    UniProtKB/TrEMBL
    A0A8C2N0F7, A0A9J7JJI6
Nucleotide Protein Strain
Heading Accession and Version

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