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Dock1 dedicator of cytokinesis 1 [ Cavia porcellus (domestic guinea pig) ]

Gene ID: 100734315, updated on 6-Jun-2024

Summary

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Gene symbol
Dock1
Gene description
dedicator of cytokinesis 1
See related
Ensembl:ENSCPOG00000015495
Gene type
protein coding
RefSeq status
MODEL
Organism
Cavia porcellus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
52
Annotation release Status Assembly Chr Location
RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947485.1 (99767385..100283417)
103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176418.1 (40662637..41179121, complement)

NW_026947485.1Genomic Context describing neighboring genes Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like Neighboring gene eukaryotic translation initiation factor 2 subunit 2-like Neighboring gene inhibitory synaptic factor 2A Neighboring gene neuropeptide S Neighboring gene forkhead box I2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables small GTPase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in myoblast fusion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dedicator of cytokinesis protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCavPor4.1

Genomic

  1. NW_026947485.1 Reference mCavPor4.1

    Range
    99767385..100283417
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013143418.3 → XP_012998872.1  dedicator of cytokinesis protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A286XSG8
    Conserved Domains (4) summary
    cd08694
    Location:445 → 640
    C2_Dock-A; C2 domains found in Dedicator Of CytoKinesis (Dock) class A proteins
    cd11707
    Location:1235 → 1633
    DHR2_DOCK1; Dock Homology Region 2, a GEF domain, of Class A Dedicator of Cytokinesis 1
    cd12051
    Location:13 → 68
    SH3_DOCK1_5_A; Src Homology 3 domain of Class A Dedicator of Cytokinesis proteins 1 and 5
    pfam16172
    Location:72 → 437
    DOCK_N; DOCK N-terminus

  2. XM_063244929.1 → XP_063100999.1  dedicator of cytokinesis protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A286XSG8

  3. XM_003479612.5 → XP_003479660.2  dedicator of cytokinesis protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A286XSG8, H0VTH6
    Related
    ENSCPOP00000013973.2
    Conserved Domains (4) summary
    cd08694
    Location:424 → 619
    C2_Dock-A; C2 domains found in Dedicator Of CytoKinesis (Dock) class A proteins
    cd11707
    Location:1214 → 1612
    DHR2_DOCK1; Dock Homology Region 2, a GEF domain, of Class A Dedicator of Cytokinesis 1
    cd12051
    Location:13 → 68
    SH3_DOCK1_5_A; Src Homology 3 domain of Class A Dedicator of Cytokinesis proteins 1 and 5
    pfam16172
    Location:72 → 416
    DOCK_N; DOCK N-terminus
Nucleotide Protein
Heading Accession and Version

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