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Prf1 perforin 1 [ Cavia porcellus (domestic guinea pig) ]

Gene ID: 100730283, updated on 8-Mar-2024

Summary

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Gene symbol
Prf1
Gene description
perforin 1
See related
Ensembl:ENSCPOG00000033631
Gene type
protein coding
RefSeq status
MODEL
Organism
Cavia porcellus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
Orthologs
human mouse all
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Genomic context

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See Prf1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947511.1 (28897966..28902394, complement)
103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176404.1 (19924195..19928572, complement)

NW_026947511.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111757973 Neighboring gene nodal growth differentiation factor Neighboring gene phosphatase domain containing paladin 1 Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 14 Neighboring gene thymus, brain and testes associated

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pore-forming activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables wide pore channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in T cell mediated cytotoxicity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response to virus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immunological synapse formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
perforin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCavPor4.1

Genomic

  1. NW_026947511.1 Reference mCavPor4.1

    Range
    28897966..28902394 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003473749.4 → XP_003473797.1  perforin-1

    UniProtKB/TrEMBL
    A0A286XXN8
    Related
    ENSCPOP00000030304.1
    Conserved Domains (2) summary
    cd04032
    Location:389 → 513
    C2_Perforin; C2 domain of Perforin
    smart00457
    Location:166 → 368
    MACPF; membrane-attack complex / perforin
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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