Pkp2 plakophilin 2 [Cavia porcellus (domestic guinea pig)] - Gene

Summary

Gene symbol: Pkp2
Gene description: plakophilin 2
See related: Ensembl:ENSCPOG00000012340
Gene type: protein coding
RefSeq status: MODEL
Organism: Cavia porcellus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	mCavPor4.1 (GCF_034190915.1)	Unplaced Scaffold	NW_026947491.1 (28504996..28584468, complement)
103	previous assembly	Cavpor3.0 (GCF_000151735.1)	Unplaced Scaffold	NT_176365.1 (3279264..3358738)

NW_026947491.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Function	Evidence Code	Pubs
enables alpha-catenin binding	IEA Inferred from Electronic Annotation more info	PubMed
enables cadherin binding	IEA Inferred from Electronic Annotation more info	PubMed
enables intermediate filament binding	IEA Inferred from Electronic Annotation more info	PubMed
enables molecular adaptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein kinase C binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell-cell adhesion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cell-cell junction assembly	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cell-cell signaling involved in cardiac conduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in desmosome organization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in heart development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in intermediate filament bundle assembly	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein localization to plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in adherens junction	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in intercalated disc	IEA Inferred from Electronic Annotation more info	PubMed
located_in intermediate filament	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

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The following sections contain reference sequences that belong to a specific genome build. Explain

XM_003466762.5 → XP_003466810.2 plakophilin-2 isoform X1

UniProtKB/TrEMBL

H0VL79
XM_063254534.1 → XP_063110604.1 plakophilin-2 isoform X2

UniProtKB/TrEMBL

H0VL79
XM_063254535.1 → XP_063110605.1 plakophilin-2 isoform X3

UniProtKB/TrEMBL

H0VL79