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pgpep1 pyroglutamyl-peptidase I [ Oreochromis niloticus (Nile tilapia) ]

Gene ID: 100709617, updated on 8-Mar-2024

Summary

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Gene symbol
pgpep1
Gene description
pyroglutamyl-peptidase I
See related
Ensembl:ENSONIG00000027578
Gene type
protein coding
RefSeq status
MODEL
Organism
Oreochromis niloticus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini; Oreochromis
Expression
Ubiquitous expression in testis (RPKM 5.1), kidney (RPKM 4.9) and 9 other tissues See more
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: LG15
Exon count:
5
Annotation release Status Assembly LG Location
104 current O_niloticus_UMD_NMBU (GCF_001858045.2) LG15 NC_031980.2 (32127783..32136390, complement)
103 previous assembly ASM185804v2 (GCF_001858045.1) LG15 NC_031980.1 (19212862..19221472, complement)

Linkage Group LG15 - NC_031980.2Genomic Context describing neighboring genes Neighboring gene homer scaffold protein 3 Neighboring gene DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 Neighboring gene UPF1 RNA helicase and ATPase Neighboring gene E3 ubiquitin-protein ligase rnf213-alpha Neighboring gene LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables pyroglutamyl-peptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pyroglutamyl-peptidase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Oreochromis niloticus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference O_niloticus_UMD_NMBU Primary Assembly

Genomic

  1. NC_031980.2 Reference O_niloticus_UMD_NMBU Primary Assembly

    Range
    32127783..32136390 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003449082.5 → XP_003449130.1  pyroglutamyl-peptidase 1

    UniProtKB/TrEMBL
    A0A669D0I2, A0A669DI04
    Related
    ENSONIP00000054083.1, ENSONIT00000035662.1
    Conserved Domains (1) summary
    cd00501
    Location:8 → 199
    Peptidase_C15; Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I: Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from ...
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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