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LOC100691159 WNK lysine deficient protein kinase 2 [ Oreochromis niloticus (Nile tilapia) ]

Gene ID: 100691159, updated on 21-Dec-2023

Summary

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Gene symbol
LOC100691159
Gene description
WNK lysine deficient protein kinase 2
See related
Ensembl:ENSONIG00000017202
Gene type
protein coding
RefSeq status
MODEL
Organism
Oreochromis niloticus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini; Oreochromis
Also known as
wnk2
Expression
Biased expression in eye (RPKM 10.8), brain (RPKM 7.3) and 3 other tissues See more
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Genomic context

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See LOC100691159 in Genome Data Viewer
Location:
chromosome: LG20
Exon count:
30
Annotation release Status Assembly LG Location
104 current O_niloticus_UMD_NMBU (GCF_001858045.2) LG20 NC_031984.2 (14265869..14307061)
103 previous assembly ASM185804v2 (GCF_001858045.1) LG20 NC_031984.1 (14767776..14808968)

Linkage Group LG20 - NC_031984.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100690351 Neighboring gene caspase recruitment domain-containing protein 19 Neighboring gene ninjurin-1 Neighboring gene bromodomain and PHD finger containing, 1 Neighboring gene interleukin 17 receptor E

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Oreochromis niloticus Transcriptome or Gene expression Oreochromis niloticus Transcriptome or Gene expression
  • Description: Oreochromis niloticus (Nile Tilapia) RNA sequencing from multiple tissues.
  • BioProject: PRJNA78915
  • Analysis date: Fri Dec 29 00:23:36 2017

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables chloride channel inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables potassium channel inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in monoatomic ion homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of sodium ion transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of potassium ion import across plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of sodium ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase WNK2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Oreochromis niloticus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference O_niloticus_UMD_NMBU Primary Assembly

Genomic

  1. NC_031984.2 Reference O_niloticus_UMD_NMBU Primary Assembly

    Range
    14265869..14307061
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019349642.1 → XP_019205187.1  serine/threonine-protein kinase WNK2 isoform X1

    UniProtKB/TrEMBL
    I3KKQ5

  2. XM_019349647.1 → XP_019205192.1  serine/threonine-protein kinase WNK2 isoform X5

  3. XM_019349645.1 → XP_019205190.1  serine/threonine-protein kinase WNK2 isoform X3

  4. XM_019349646.1 → XP_019205191.1  serine/threonine-protein kinase WNK2 isoform X4

  5. XM_019349648.1 → XP_019205193.1  serine/threonine-protein kinase WNK2 isoform X6

  6. XM_019349649.1 → XP_019205194.1  serine/threonine-protein kinase WNK2 isoform X7

  7. XM_019349644.1 → XP_019205189.1  serine/threonine-protein kinase WNK2 isoform X2

  8. XM_025901825.1 → XP_025757610.1  serine/threonine-protein kinase WNK2 isoform X8

    Conserved Domains (4) summary
    cd13983
    Location:179 → 439
    STKc_WNK; Catalytic domain of the Serine/Threonine kinase, With No Lysine (WNK) kinase
    pfam12202
    Location:460 → 497
    OSR1_C; Oxidative-stress-responsive kinase 1 C terminal
    cl25764
    Location:1035 → 1190
    PAT1; Topoisomerase II-associated protein PAT1
    cl28087
    Location:557 → 983
    FtsK; DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell cycle control, cell division, chromosome partitioning]

  9. XM_019349643.1 → XP_019205188.1  serine/threonine-protein kinase WNK2 isoform X1

    UniProtKB/TrEMBL
    I3KKQ5
    Related
    ENSONIP00000021700.2, ENSONIT00000021719.2
Nucleotide Protein
Heading Accession and Version

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