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SH2B1 SH2B adaptor protein 1 [ Loxodonta africana (African savanna elephant) ]

Gene ID: 100676735, updated on 11-Apr-2024

Summary

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Gene symbol
SH2B1
Gene description
SH2B adaptor protein 1
See related
EnsemblRapid:ENSLAFG00000016709
Gene type
protein coding
RefSeq status
MODEL
Organism
Loxodonta africana
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 12
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_04 current mLoxAfr1.hap2 (GCF_030014295.1) 12 NC_087353.1 (84967839..84976733, complement)
102 previous assembly Loxafr3.0 (GCF_000001905.1) Unplaced Scaffold NW_003573485.1 (10733029..10742721, complement)

Chromosome 12 - NC_087353.1Genomic Context describing neighboring genes Neighboring gene rabaptin, RAB GTPase binding effector protein 2 Neighboring gene ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 Neighboring gene Tu translation elongation factor, mitochondrial Neighboring gene ataxin 2 like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables transmembrane receptor protein tyrosine kinase adaptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
SH2B adapter protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030014295.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mLoxAfr1.hap2

Genomic

  1. NC_087353.1 Reference mLoxAfr1.hap2

    Range
    84967839..84976733 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010598486.3 → XP_010596788.1  SH2B adapter protein 1 isoform X4

    See identical proteins and their annotated locations for XP_010596788.1

    UniProtKB/TrEMBL
    G3THH9
    Related
    ENSLAFP00000035005.1, ENSLAFT00000062382.1
    Conserved Domains (3) summary
    cd10346
    Location:518 → 614
    SH2_SH2B_family; Src homology 2 (SH2) domain found in SH2B adapter protein family
    cd01231
    Location:246 → 378
    PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
    pfam08916
    Location:26 → 81
    Phe_ZIP; Phenylalanine zipper

  2. XM_023558891.2 → XP_023414659.1  SH2B adapter protein 1 isoform X1

    Conserved Domains (3) summary
    cd10346
    Location:518 → 614
    SH2_SH2B_family; Src homology 2 (SH2) domain found in SH2B adapter protein family
    cd01231
    Location:246 → 378
    PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
    pfam08916
    Location:26 → 81
    Phe_ZIP; Phenylalanine zipper

  3. XM_023558893.2 → XP_023414661.1  SH2B adapter protein 1 isoform X3

    Conserved Domains (3) summary
    cd10346
    Location:518 → 614
    SH2_SH2B_family; Src homology 2 (SH2) domain found in SH2B adapter protein family
    cd01231
    Location:246 → 378
    PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
    pfam08916
    Location:26 → 81
    Phe_ZIP; Phenylalanine zipper

  4. XM_064295784.1 → XP_064151854.1  SH2B adapter protein 1 isoform X5

  5. XM_023558892.2 → XP_023414660.1  SH2B adapter protein 1 isoform X2

    Related
    ENSLAFP00000014023.4, ENSLAFT00000016709.4
    Conserved Domains (3) summary
    cd10346
    Location:518 → 614
    SH2_SH2B_family; Src homology 2 (SH2) domain found in SH2B adapter protein family
    cd01231
    Location:246 → 378
    PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
    pfam08916
    Location:26 → 81
    Phe_ZIP; Phenylalanine zipper
Nucleotide Protein
Heading Accession and Version

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