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SMAD9 SMAD family member 9 [ Loxodonta africana (African savanna elephant) ]

Gene ID: 100676711, updated on 11-Apr-2024

Summary

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Gene symbol
SMAD9
Gene description
SMAD family member 9
See related
EnsemblRapid:ENSLAFG00000002903
Gene type
protein coding
RefSeq status
MODEL
Organism
Loxodonta africana
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 17
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_04 current mLoxAfr1.hap2 (GCF_030014295.1) 17 NC_087358.1 (81412973..81614968)
102 previous assembly Loxafr3.0 (GCF_000001905.1) Unplaced Scaffold NW_003573443.1 (41790479..41991848)

Chromosome 17 - NC_087358.1Genomic Context describing neighboring genes Neighboring gene SPT20 homolog, SAGA complex component Neighboring gene uncharacterized LOC135227999 Neighboring gene exosome component 8 Neighboring gene ALG5 dolichyl-phosphate beta-glucosyltransferase Neighboring gene regulatory factor X associated protein Neighboring gene CCR4-NOT transcription complex subunit 11-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables I-SMAD binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in BMP signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in SMAD protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in anatomical structure morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in transforming growth factor beta receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of heteromeric SMAD protein complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mothers against decapentaplegic homolog 9

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030014295.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mLoxAfr1.hap2

Genomic

  1. NC_087358.1 Reference mLoxAfr1.hap2

    Range
    81412973..81614968
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010592667.3 → XP_010590969.1  mothers against decapentaplegic homolog 9 isoform X2

    UniProtKB/TrEMBL
    G3SRC3
    Related
    ENSLAFP00000034227.1, ENSLAFT00000052303.1
    Conserved Domains (2) summary
    cd10490
    Location:13 → 136
    MH1_SMAD_1_5_9; N-terminal Mad Homology 1 (MH1) domain in SMAD1, SMAD5 and SMAD9 (also known as SMAD8)
    cl00056
    Location:230 → 430
    MH2; C-terminal Mad Homology 2 (MH2) domain

  2. XM_064270246.1 → XP_064126316.1  mothers against decapentaplegic homolog 9 isoform X1

  3. XM_064270248.1 → XP_064126318.1  mothers against decapentaplegic homolog 9 isoform X1

  4. XM_064270247.1 → XP_064126317.1  mothers against decapentaplegic homolog 9 isoform X1

  5. XM_010592664.3 → XP_010590966.1  mothers against decapentaplegic homolog 9 isoform X1

    See identical proteins and their annotated locations for XP_010590966.1

    Conserved Domains (2) summary
    cd10490
    Location:13 → 136
    MH1_SMAD_1_5_9; N-terminal Mad Homology 1 (MH1) domain in SMAD1, SMAD5 and SMAD9 (also known as SMAD8)
    cl00056
    Location:266 → 466
    MH2; C-terminal Mad Homology 2 (MH2) domain

  6. XM_023551376.2 → XP_023407144.1  mothers against decapentaplegic homolog 9 isoform X1

    Related
    ENSLAFP00000002424.4, ENSLAFT00000002903.4
    Conserved Domains (2) summary
    cd10490
    Location:13 → 136
    MH1_SMAD_1_5_9; N-terminal Mad Homology 1 (MH1) domain in SMAD1, SMAD5 and SMAD9 (also known as SMAD8)
    cl00056
    Location:266 → 466
    MH2; C-terminal Mad Homology 2 (MH2) domain

RNA

  1. XR_002786430.2 RNA Sequence

Nucleotide Protein
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