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DDB2 damage specific DNA binding protein 2 [ Loxodonta africana (African savanna elephant) ]

Gene ID: 100665802, updated on 11-Apr-2024

Summary

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Gene symbol
DDB2
Gene description
damage specific DNA binding protein 2
See related
EnsemblRapid:ENSLAFG00000009262
Gene type
protein coding
RefSeq status
MODEL
Organism
Loxodonta africana
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 7
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_04 current mLoxAfr1.hap2 (GCF_030014295.1) 7 NC_087348.1 (35818187..35844902, complement)
102 previous assembly Loxafr3.0 (GCF_000001905.1) Unplaced Scaffold NW_003573441.1 (2279260..2294936, complement)

Chromosome 7 - NC_087348.1Genomic Context describing neighboring genes Neighboring gene MAP kinase activating death domain Neighboring gene nuclear receptor subfamily 1 group H member 3 Neighboring gene acid phosphatase 2, lysosomal Neighboring gene protein kinase C and casein kinase substrate in neurons 3 Neighboring gene ADP ribosylation factor GTPase activating protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables damaged DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to UV IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of Cul4-RING E3 ubiquitin ligase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA damage-binding protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030014295.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mLoxAfr1.hap2

Genomic

  1. NC_087348.1 Reference mLoxAfr1.hap2

    Range
    35818187..35844902 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023550649.2 → XP_023406417.1  DNA damage-binding protein 2 isoform X1

    UniProtKB/TrEMBL
    G3T3E5
    Related
    ENSLAFP00000007762.4, ENSLAFT00000009263.4
    Conserved Domains (2) summary
    sd00039
    Location:115 → 154
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:115 → 419
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. XM_010592079.3 → XP_010590381.1  DNA damage-binding protein 2 isoform X3

    UniProtKB/TrEMBL
    G3T3E5
    Related
    ENSLAFP00000033642.1, ENSLAFT00000038325.1
    Conserved Domains (3) summary
    COG2319
    Location:92 → 355
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:96 → 135
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:83 → 355
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  3. XM_023550650.2 → XP_023406418.1  DNA damage-binding protein 2 isoform X2

    UniProtKB/TrEMBL
    G3T3E5
    Conserved Domains (2) summary
    sd00039
    Location:115 → 154
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:115 → 364
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RNA

  1. XR_010322440.1 RNA Sequence

  2. XR_010322441.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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