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CRYAA crystallin alpha A [ Nomascus leucogenys (northern white-cheeked gibbon) ]

Gene ID: 100599220, updated on 8-Mar-2024

Summary

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Gene symbol
CRYAA
Gene description
crystallin alpha A
See related
EnsemblRapid:ENSNLEG00000014752
Gene type
protein coding
RefSeq status
MODEL
Organism
Nomascus leucogenys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 25
Exon count:
10
Annotation release Status Assembly Chr Location
103 current Asia_NLE_v1 (GCF_006542625.1) 25 NC_044405.1 (28081111..28141056)
102 previous assembly Nleu_3.0 (GCF_000146795.2) 25 NC_019840.1 (29367432..29371651)

Chromosome 25 - NC_044405.1Genomic Context describing neighboring genes Neighboring gene cystathionine beta-synthase Neighboring gene 39S ribosomal protein L51, mitochondrial pseudogene Neighboring gene U2 small nuclear RNA auxiliary factor 1 Neighboring gene putative uncharacterized protein encoded by LINC00322 Neighboring gene salt inducible kinase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein folding chaperone IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables structural constituent of eye lens IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lens development in camera-type eye IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein refolding IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to heat IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
alpha-crystallin A chain

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Asia_NLE_v1 Primary Assembly

Genomic

  1. NC_044405.1 Reference Asia_NLE_v1 Primary Assembly

    Range
    28081111..28141056
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030806052.1 → XP_030661912.1  alpha-crystallin A chain isoform X1

    UniProtKB/TrEMBL
    G1RXG3
    Conserved Domains (2) summary
    cd06497
    Location:60 → 145
    ACD_alphaA-crystallin_HspB4; Alpha-crystallin domain found in the small heat shock protein (sHsp) alphaA-crystallin (HspB4, 20kDa). sHsps are molecular chaperones that suppress protein aggregation and protect against cell stress, and are generally active as large oligomers ...
    pfam00525
    Location:1 → 51
    Crystallin; Alpha crystallin A chain, N terminal

  2. XM_030806055.1 → XP_030661915.1  alpha-crystallin A chain isoform X1

    UniProtKB/TrEMBL
    G1RXG3
    Related
    ENSNLEP00000017940.3, ENSNLET00000018833.4
    Conserved Domains (2) summary
    cd06497
    Location:60 → 145
    ACD_alphaA-crystallin_HspB4; Alpha-crystallin domain found in the small heat shock protein (sHsp) alphaA-crystallin (HspB4, 20kDa). sHsps are molecular chaperones that suppress protein aggregation and protect against cell stress, and are generally active as large oligomers ...
    pfam00525
    Location:1 → 51
    Crystallin; Alpha crystallin A chain, N terminal

  3. XM_030806053.1 → XP_030661913.1  alpha-crystallin A chain isoform X1

    UniProtKB/TrEMBL
    G1RXG3
    Conserved Domains (2) summary
    cd06497
    Location:60 → 145
    ACD_alphaA-crystallin_HspB4; Alpha-crystallin domain found in the small heat shock protein (sHsp) alphaA-crystallin (HspB4, 20kDa). sHsps are molecular chaperones that suppress protein aggregation and protect against cell stress, and are generally active as large oligomers ...
    pfam00525
    Location:1 → 51
    Crystallin; Alpha crystallin A chain, N terminal

  4. XM_030806054.1 → XP_030661914.1  alpha-crystallin A chain isoform X1

    UniProtKB/TrEMBL
    G1RXG3
    Conserved Domains (2) summary
    cd06497
    Location:60 → 145
    ACD_alphaA-crystallin_HspB4; Alpha-crystallin domain found in the small heat shock protein (sHsp) alphaA-crystallin (HspB4, 20kDa). sHsps are molecular chaperones that suppress protein aggregation and protect against cell stress, and are generally active as large oligomers ...
    pfam00525
    Location:1 → 51
    Crystallin; Alpha crystallin A chain, N terminal

  5. XM_030806056.1 → XP_030661916.1  alpha-crystallin A chain isoform X2

    UniProtKB/TrEMBL
    A0A2I3HLQ4
    Related
    ENSNLEP00000044442.1, ENSNLET00000048437.2
    Conserved Domains (1) summary
    cl00175
    Location:26 → 108
    alpha-crystallin-Hsps_p23-like; alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.
Nucleotide Protein
Heading Accession and Version

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