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CREBBP CREB binding protein [ Nomascus leucogenys (northern white-cheeked gibbon) ]

Gene ID: 100596998, updated on 8-Mar-2024

Summary

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Gene symbol
CREBBP
Gene description
CREB binding protein
See related
EnsemblRapid:ENSNLEG00000009748
Gene type
protein coding
RefSeq status
MODEL
Organism
Nomascus leucogenys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 18
Exon count:
31
Annotation release Status Assembly Chr Location
103 current Asia_NLE_v1 (GCF_006542625.1) 18 NC_044398.1 (99225764..99382226)
102 previous assembly Nleu_3.0 (GCF_000146795.2) 18 NC_019833.1 (101096348..101253552)

Chromosome 18 - NC_044398.1Genomic Context describing neighboring genes Neighboring gene acyl-CoA-binding protein pseudogene Neighboring gene adenylate cyclase 9 Neighboring gene TNF receptor associated protein 1 Neighboring gene deoxyribonuclease 1 Neighboring gene SLX4 structure-specific endonuclease subunit

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables chromatin DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone acetyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription coactivator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of histone acetyltransferase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of transcription regulator complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
CREB-binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Asia_NLE_v1 Primary Assembly

Genomic

  1. NC_044398.1 Reference Asia_NLE_v1 Primary Assembly

    Range
    99225764..99382226
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003269219.4 → XP_003269267.1  CREB-binding protein isoform X1

    See identical proteins and their annotated locations for XP_003269267.1

    UniProtKB/TrEMBL
    G1RFB2
    Related
    ENSNLEP00000011912.1, ENSNLET00000012494.4
    Conserved Domains (11) summary
    cd05495
    Location:1087 → 1194
    Bromo_cbp_like; Bromodomain, cbp_like subfamily. Cbp (CREB binding protein or CREBBP) is an acetyltransferase acting on histone, which gives a specific tag for transcriptional activation and also acetylates non-histone proteins. CREBBP binds specifically to ...
    smart00551
    Location:1766 → 1844
    ZnF_TAZ; TAZ zinc finger, present in p300 and CBP
    PHA03247
    Location:683 → 1025
    PHA03247; large tegument protein UL36; Provisional
    cd02337
    Location:1705 → 1745
    ZZ_CBP; Zinc finger, ZZ type. Zinc finger present in CBP/p300 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. CREB-binding protein (CBP) is a large multidomain protein that ...
    cd15802
    Location:1206 → 1278
    RING_CBP-p300; atypical RING domain found in CREB-binding protein and p300 histone acetyltransferases
    cd15557
    Location:1280 → 1311
    PHD_CBP_p300; PHD finger found in CREB-binding protein (CBP) and histone acetyltransferase p300
    pfam09606
    Location:1960 → 2423
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam02135
    Location:363 → 430
    zf-TAZ; TAZ zinc finger
    pfam02172
    Location:587 → 667
    KIX; KIX domain
    pfam08214
    Location:1342 → 1553
    HAT_KAT11; Histone acetylation protein
    pfam09030
    Location:2034 → 2114
    Creb_binding; Creb binding

  2. XM_012497415.2 → XP_012352869.1  CREB-binding protein isoform X2

    UniProtKB/TrEMBL
    A0A2I3H346
    Related
    ENSNLEP00000037925.1, ENSNLET00000051146.2
    Conserved Domains (11) summary
    cd05495
    Location:1049 → 1156
    Bromo_cbp_like; Bromodomain, cbp_like subfamily. Cbp (CREB binding protein or CREBBP) is an acetyltransferase acting on histone, which gives a specific tag for transcriptional activation and also acetylates non-histone proteins. CREBBP binds specifically to ...
    smart00551
    Location:1728 → 1806
    ZnF_TAZ; TAZ zinc finger, present in p300 and CBP
    PHA03247
    Location:645 → 987
    PHA03247; large tegument protein UL36; Provisional
    cd02337
    Location:1667 → 1707
    ZZ_CBP; Zinc finger, ZZ type. Zinc finger present in CBP/p300 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. CREB-binding protein (CBP) is a large multidomain protein that ...
    cd15802
    Location:1168 → 1240
    RING_CBP-p300; atypical RING domain found in CREB-binding protein and p300 histone acetyltransferases
    cd15557
    Location:1242 → 1273
    PHD_CBP_p300; PHD finger found in CREB-binding protein (CBP) and histone acetyltransferase p300
    pfam09606
    Location:1922 → 2385
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam02135
    Location:363 → 405
    zf-TAZ; TAZ zinc finger
    pfam02172
    Location:549 → 629
    KIX; KIX domain
    pfam08214
    Location:1304 → 1515
    HAT_KAT11; Histone acetylation protein
    pfam09030
    Location:1996 → 2076
    Creb_binding; Creb binding
Nucleotide Protein
Heading Accession and Version

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