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llgl2 LLGL scribble cell polarity complex component 2 [ Anolis carolinensis (green anole) ]

Gene ID: 100564177, updated on 8-Mar-2024

Summary

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Gene symbol
llgl2
Gene description
LLGL scribble cell polarity complex component 2
See related
Ensembl:ENSACAG00000006728
Gene type
protein coding
RefSeq status
MODEL
Organism
Anolis carolinensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Iguania; Dactyloidae; Anolis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2024_02 current rAnoCar3.1.pri (GCF_035594765.1) 2 NC_085842.1 (135138320..135215758)
102 previous assembly AnoCar2.0 (GCF_000090745.1) 2 NC_014777.1 (114032084..114109333, complement)

Chromosome 2 - NC_085842.1Genomic Context describing neighboring genes Neighboring gene tRNA splicing endonuclease subunit 54 Neighboring gene microRNA mir-5460 Neighboring gene uncharacterized LOC134295890 Neighboring gene uncharacterized LOC134296248 Neighboring gene unconventional myosin heavy chain 6-like Neighboring gene unconventional myosin-XVB

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables myosin II binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cortical actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of spindle orientation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of establishment or maintenance of cell polarity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of protein secretion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cortical actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LLGL scribble cell polarity complex component 2
Names
LLGL2, scribble cell polarity complex component
lethal giant larvae homolog 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_035594765.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference rAnoCar3.1.pri

Genomic

  1. NC_085842.1 Reference rAnoCar3.1.pri

    Range
    135138320..135215758
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003217208.4 → XP_003217256.1  LLGL scribble cell polarity complex component 2 isoform X1

    UniProtKB/TrEMBL
    A0A803T8R7, G1KFR8
    Related
    ENSACAP00000031607.1
    Conserved Domains (3) summary
    COG2319
    Location:45 → 263
    WD40; WD40 repeat [General function prediction only]
    pfam08366
    Location:273 → 372
    LLGL; LLGL2
    sd00039
    Location:77 → 120
    7WD40; WD40 repeat [structural motif]

  2. XM_016991344.2 → XP_016846833.1  LLGL scribble cell polarity complex component 2 isoform X1

    UniProtKB/TrEMBL
    A0A803T8R7, G1KFR8
    Related
    ENSACAP00000006651.3
    Conserved Domains (3) summary
    COG2319
    Location:45 → 263
    WD40; WD40 repeat [General function prediction only]
    pfam08366
    Location:273 → 372
    LLGL; LLGL2
    sd00039
    Location:77 → 120
    7WD40; WD40 repeat [structural motif]

  3. XM_016991345.2 → XP_016846834.1  LLGL scribble cell polarity complex component 2 isoform X2

    UniProtKB/TrEMBL
    A0A803T8R7
Nucleotide Protein
Heading Accession and Version

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