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PLEK pleckstrin [ Meleagris gallopavo (turkey) ]

Gene ID: 100550378, updated on 8-Mar-2024

Summary

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Gene symbol
PLEK
Gene description
pleckstrin
See related
Ensembl:ENSMGAG00000004436
Gene type
protein coding
RefSeq status
MODEL
Organism
Meleagris gallopavo
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Meleagridinae; Meleagris
Orthologs
human mouse all
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Genomic context

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See PLEK in Genome Data Viewer
Location:
chromosome: 2
Exon count:
12
Annotation release Status Assembly Chr Location
103 current Turkey_5.1 (GCF_000146605.3) 2 NC_015012.2 (5696891..5750169, complement)
Build 1.1 previous assembly Turkey_2.01 (GCF_000146605.1) 2 NC_015012.1 (6127596..6142458, complement)

Chromosome 2 - NC_015012.2Genomic Context describing neighboring genes Neighboring gene aprataxin and PNKP like factor Neighboring gene F-box protein 48 Neighboring gene cannabinoid receptor interacting protein 1 Neighboring gene protein phosphatase 3 regulatory subunit B, alpha Neighboring gene partner of NOB1 homolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pleckstrin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Meleagris gallopavo Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Turkey_5.1 Primary Assembly

Genomic

  1. NC_015012.2 Reference Turkey_5.1 Primary Assembly

    Range
    5696891..5750169 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010706438.3 → XP_010704740.1  pleckstrin isoform X3

    UniProtKB/TrEMBL
    A0A803YGU1, G1MZ14
    Related
    ENSMGAP00000030988.1, ENSMGAT00000031584.1
    Conserved Domains (3) summary
    cd04445
    Location:109 → 207
    DEP_PLEK1; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in pleckstrin 1-like proteins. Pleckstrin 1 plays a role in cell spreading and reorganization of actin cytoskeleton in platelets and leukocytes. Its activity is highly regulated by phosphorylation, ...
    cd13301
    Location:1 → 94
    PH1_Pleckstrin_2; Pleckstrin 2 Pleckstrin homology (PH) domain, repeat 1
    cd13302
    Location:223 → 331
    PH2_Pleckstrin_2; Pleckstrin 2 Pleckstrin homology (PH) domain, repeat 2

  2. XM_019612542.2 → XP_019468087.1  pleckstrin isoform X2

    UniProtKB/TrEMBL
    A0A803YP18, G1MZ14
    Related
    ENSMGAP00000033516.1, ENSMGAT00000024536.1
    Conserved Domains (3) summary
    cd04445
    Location:127 → 225
    DEP_PLEK1; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in pleckstrin 1-like proteins. Pleckstrin 1 plays a role in cell spreading and reorganization of actin cytoskeleton in platelets and leukocytes. Its activity is highly regulated by phosphorylation, ...
    cd13301
    Location:13 → 112
    PH1_Pleckstrin_2; Pleckstrin 2 Pleckstrin homology (PH) domain, repeat 1
    cd13302
    Location:241 → 349
    PH2_Pleckstrin_2; Pleckstrin 2 Pleckstrin homology (PH) domain, repeat 2

  3. XM_003203684.4 → XP_003203732.1  pleckstrin isoform X1

    UniProtKB/TrEMBL
    A0A803XKZ8, A0A803XYH7
    Related
    ENSMGAP00000024573.1, ENSMGAT00000026514.1
    Conserved Domains (3) summary
    cd04445
    Location:127 → 225
    DEP_PLEK1; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in pleckstrin 1-like proteins. Pleckstrin 1 plays a role in cell spreading and reorganization of actin cytoskeleton in platelets and leukocytes. Its activity is highly regulated by phosphorylation, ...
    cd13301
    Location:5 → 112
    PH1_Pleckstrin_2; Pleckstrin 2 Pleckstrin homology (PH) domain, repeat 1
    cd13302
    Location:241 → 349
    PH2_Pleckstrin_2; Pleckstrin 2 Pleckstrin homology (PH) domain, repeat 2
Nucleotide Protein
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